Relations between the capacity of thymic repeopling and the formation of lymphoma obtained by radiation-induced preleukemic cells in C57BL/Ka mice

We have analyzed the repopulation of thymuses injected with preleukemic cells obtained at various interval after fractionated irradiation. Our results show that preleukemic cells can repopulate the thymus transiently as normal thymocytes or they can proliferate in recipients. In all cases, preleukemic cells can give rise to donor lymphomas