Previous studies have described the presence of glycine receptor mRNA during early stages of embryonic cortex development. Here, we have tested the functionality of those receptors in migratory interneurons and demonstrated their involvement in the control of cell migration. We suggest a mechanism whereby activation of glycine receptors during tangential migration activates voltage gated calcium channels and favors influx of calcium that ultimately affect myosin II activity, a mechanism that fine tune nuclear translocation and thus migration speed
The development of the cerebral cortex requires coordinated regulation of proliferation, specificati...
Glycine is an inhibitory neurotransmitter acting mainly in the caudal part of the central nervous sy...
International audienceMigration of neurons from their birthplace to their final destination is an ex...
SummaryGlycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their...
Glycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their functi...
Glycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their functi...
SummaryGlycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their...
This study focuses on glycine receptors (GlyR) and explores their possible physiological functions o...
The strychnine-sensitive glycine receptor (GlyR) is a member of the ligand-gated ion channel superfa...
Using fluo-3 calcium imaging, we demonstrate that glycine induces an increase in intracellular calci...
The strychnine-sensitive glycine receptor (GlyR) is a member of the ligand-gated ion channel superfa...
<p>Various neurotransmitters influence neuronal migration in the developing zebrafish hindbrain. Mig...
Various neurotransmitters influence neuronal migration in the developing zebrafish hindbrain. Migrat...
The inhibitory neurotransmitter glycine is known to enhance microglial nitric oxide production. Howe...
Inhibitory glycine receptors (GlyRs) are mainly expressed in the spinal cord and in the midbrain, wh...
The development of the cerebral cortex requires coordinated regulation of proliferation, specificati...
Glycine is an inhibitory neurotransmitter acting mainly in the caudal part of the central nervous sy...
International audienceMigration of neurons from their birthplace to their final destination is an ex...
SummaryGlycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their...
Glycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their functi...
Glycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their functi...
SummaryGlycine receptors (GlyRs) are detected in the developing CNS before synaptogenesis, but their...
This study focuses on glycine receptors (GlyR) and explores their possible physiological functions o...
The strychnine-sensitive glycine receptor (GlyR) is a member of the ligand-gated ion channel superfa...
Using fluo-3 calcium imaging, we demonstrate that glycine induces an increase in intracellular calci...
The strychnine-sensitive glycine receptor (GlyR) is a member of the ligand-gated ion channel superfa...
<p>Various neurotransmitters influence neuronal migration in the developing zebrafish hindbrain. Mig...
Various neurotransmitters influence neuronal migration in the developing zebrafish hindbrain. Migrat...
The inhibitory neurotransmitter glycine is known to enhance microglial nitric oxide production. Howe...
Inhibitory glycine receptors (GlyRs) are mainly expressed in the spinal cord and in the midbrain, wh...
The development of the cerebral cortex requires coordinated regulation of proliferation, specificati...
Glycine is an inhibitory neurotransmitter acting mainly in the caudal part of the central nervous sy...
International audienceMigration of neurons from their birthplace to their final destination is an ex...