Cyclin E1 is expressed during the late G1 phase of the cell cycle and mediates the initiation of DNA synthesis by activating cyclin-dependent kinases 2 (CDK2). Abnormally high levels of cyclin E1 expression have frequently been found in cancer cells. Here, we investigate the effect of cyclin E1 knockdown on cancer cells.info:eu-repo/semantics/publishe
Cell cycle progression is tightly regulated in normal eucaryotic cells. Cancer is caused by the tran...
Hepatocellular carcinoma (HCC) accounts for 70-85% of liver cancer, which is the sixth most common c...
Cyclin E, in complex with cyclin dependent kinase 2 (CDK2), is a positive regulator of G1 to S phase...
AbstractG1 is the phase of the cell cycle wherein the cell is responsive to growth factor-dependent ...
Cyclin E, a regulatory subunit of cyclin-dependent kinase 2 (CDK2), is central to the initiation of ...
Cyclin E, a positive regulatory subunit of Cdk2, normally accumulates periodically at the G1/S trans...
Cell cycle deregulation and genomic instabil-ity play a major role in the aberrant cell pro-liferati...
Abstract Cyclins are indispensable elements of the cell cycle and derangement of their function can ...
Cyclin E, a positive regulatory subunit of Cdk2, normally accumulates periodically at the G1-S trans...
Simple Summary: The cell cycle regulator Cyclin E1 is a key mediator and biomarker of liver cancer p...
Background: The cyclin E oncogene activates CDK2 to drive cells from G1 to S phase of the cell cycle...
SummaryCell-cycle progression is regulated by the cyclin-dependent kinase (Cdk) family of protein ki...
AbstractBackground: Cyclin E, in conjunction with its catalytic partner cdk2, is rate limiting for e...
International audienceThe cell cycle is tightly regulated by cyclins and their catalytic moieties, t...
Unrestrained proliferation is a hallmark of cancer and genetic defects within G1/S-phase regulation ...
Cell cycle progression is tightly regulated in normal eucaryotic cells. Cancer is caused by the tran...
Hepatocellular carcinoma (HCC) accounts for 70-85% of liver cancer, which is the sixth most common c...
Cyclin E, in complex with cyclin dependent kinase 2 (CDK2), is a positive regulator of G1 to S phase...
AbstractG1 is the phase of the cell cycle wherein the cell is responsive to growth factor-dependent ...
Cyclin E, a regulatory subunit of cyclin-dependent kinase 2 (CDK2), is central to the initiation of ...
Cyclin E, a positive regulatory subunit of Cdk2, normally accumulates periodically at the G1/S trans...
Cell cycle deregulation and genomic instabil-ity play a major role in the aberrant cell pro-liferati...
Abstract Cyclins are indispensable elements of the cell cycle and derangement of their function can ...
Cyclin E, a positive regulatory subunit of Cdk2, normally accumulates periodically at the G1-S trans...
Simple Summary: The cell cycle regulator Cyclin E1 is a key mediator and biomarker of liver cancer p...
Background: The cyclin E oncogene activates CDK2 to drive cells from G1 to S phase of the cell cycle...
SummaryCell-cycle progression is regulated by the cyclin-dependent kinase (Cdk) family of protein ki...
AbstractBackground: Cyclin E, in conjunction with its catalytic partner cdk2, is rate limiting for e...
International audienceThe cell cycle is tightly regulated by cyclins and their catalytic moieties, t...
Unrestrained proliferation is a hallmark of cancer and genetic defects within G1/S-phase regulation ...
Cell cycle progression is tightly regulated in normal eucaryotic cells. Cancer is caused by the tran...
Hepatocellular carcinoma (HCC) accounts for 70-85% of liver cancer, which is the sixth most common c...
Cyclin E, in complex with cyclin dependent kinase 2 (CDK2), is a positive regulator of G1 to S phase...
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