Add to ORKGInterleukin-2 (IL-2) is the first lymphokine secreted following T cell activation, Several transcription factors regulate IL-2 gene expression, including the nuclear factor of activated T cells (NFAT), NFAT acts at the antigen receptor response element-2 (ARRE-2) sequence in the IL-2 enhancer and is the nuclear target of T cell stimulation signals and the immunosuppressant drugs cyclosporine and FK506, which are potent inhibitors of IL-2 gene transcription, NFAT has been cloned and found to consist of two subunits, NF45 (ILF2) and NF90 (ILF3), This communication reports the assignment of NF45, interleukin enhancer binding factor 2 gene (ILF2), to human chromosome 1 (1q11-qter and 1p11-p12) by polymerase chain reaction (PCR) amplification of...
The human interleukin 1α gene was assigned to chromosome 2 using Southern transfer analysis of human...
The 5' flanking region of the human interleukin (IL)-2 gene was investigated for enhancer activity i...
The 5' flanking region of the human interleukin (IL)-2 gene was investigated for enhancer activity i...
Interleukin-2 (IL-2) is the first lymphokine secreted following T cell activation. Several transcrip...
Interleukin-2 (IL-2) is the first lymphokine secreted following T cell activation. Several transcrip...
Interleukin-2 (IL-2), originally defined as a lymphokine which permits clonal expansion of T-cell cl...
We report here that interleukin 2 (IL-2) acts on human blood monocytes by enhancing binding activity...
Known transcription factor–DNA interactions in the minimal enhancer of the murine interleukin-2 gene...
IL-TIF is a new cytokine originally identified as a gene induced by IL-9 in murine T lymphocytes, an...
Interleukin-2 (IL-2) is a glycoprotein produced by CD4$\sp{+}$ T lymphocytes after mitogenic or anti...
The nuclear factor of activated T cells (NFAT) transcription factor is implicated in expression of t...
Known transcription factor-DNA interactions in the minimal enhancer of the murine interleukin-2 gene...
IL-TIF is a new cytokine originally identified as a gene induced by IL-9 in murine T lymphocytes, an...
Using a transient transfection assay, we have defined the sequences required for the activation of t...
The interferon regulatory factor (IRF) genes encode a family of transcription factors involved in th...
The human interleukin 1α gene was assigned to chromosome 2 using Southern transfer analysis of human...
The 5' flanking region of the human interleukin (IL)-2 gene was investigated for enhancer activity i...
The 5' flanking region of the human interleukin (IL)-2 gene was investigated for enhancer activity i...
Interleukin-2 (IL-2) is the first lymphokine secreted following T cell activation. Several transcrip...
Interleukin-2 (IL-2) is the first lymphokine secreted following T cell activation. Several transcrip...
Interleukin-2 (IL-2), originally defined as a lymphokine which permits clonal expansion of T-cell cl...
We report here that interleukin 2 (IL-2) acts on human blood monocytes by enhancing binding activity...
Known transcription factor–DNA interactions in the minimal enhancer of the murine interleukin-2 gene...
IL-TIF is a new cytokine originally identified as a gene induced by IL-9 in murine T lymphocytes, an...
Interleukin-2 (IL-2) is a glycoprotein produced by CD4$\sp{+}$ T lymphocytes after mitogenic or anti...
The nuclear factor of activated T cells (NFAT) transcription factor is implicated in expression of t...
Known transcription factor-DNA interactions in the minimal enhancer of the murine interleukin-2 gene...
IL-TIF is a new cytokine originally identified as a gene induced by IL-9 in murine T lymphocytes, an...
Using a transient transfection assay, we have defined the sequences required for the activation of t...
The interferon regulatory factor (IRF) genes encode a family of transcription factors involved in th...
The human interleukin 1α gene was assigned to chromosome 2 using Southern transfer analysis of human...
The 5' flanking region of the human interleukin (IL)-2 gene was investigated for enhancer activity i...
The 5' flanking region of the human interleukin (IL)-2 gene was investigated for enhancer activity i...