Ugi Four-Center Three-Component Reaction as a Direct Approach to Racetams

Cioc, Razvan C.
van Riempst, Lola Schaepkens
Schuckman, Peter
Ruijter, Eelco
Orru, Romano V. A.

Open link

Publication date

April 2017

DOI

10.1055/s-0036-1588672

Publisher

Georg Thieme Verlag KG

ISSN

0039-7881

Citation count (estimate)

Abstract

We report the synthesis of racetams, a diverse class of small molecule drugs, by means of the Ugi four-center three-component reaction (U4C-3CR). For the first time, γ-aminobutyric acid is employed as bifunctional input in the Ugi reaction. This protocol is simple, general, and allows one-pot access to a range of drugs and bioactive small molecules

Extracted data

We use cookies to provide a better user experience.

Data Protection

Ugi Four-Center Three-Component Reaction as a Direct Approach to Racetams

Abstract

Extracted data

Ugi Four-Center Three-Component Reaction as a Direct Approach to Racetams

Abstract

Extracted data

Related items

Related items