'Leukodystrophy‐like' phenotype in children with myelin oligodendrocyte glycoprotein antibody‐associated disease

Aim: To review the demographics and clinical and paraclinical parameters of children with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated relapsing disease. / Method: In this UK‐based, multicentre study, 31 children with MOG antibody‐associated relapsing disease were studied retrospectively. / Results: Of the 31 children studied, 14 presented with acute disseminated encephalomyelitis (ADEM); they were younger (mean 4.1y) than the remainder (mean 8.5y) who presented with optic neuritis and/or transverse myelitis (p<0.001). Similarly, children who had an abnormal brain magnetic resonance imaging (MRI) at onset (n=20) were younger than patients with normal MRI at onset (p=0.001) or at follow‐up (p