Add to ORKGThe invention provides highly functionalised spiro-fused azetidinones of formula (I) having a cyclohexane moiety with the desired number of protected or unprotected hydroxyl groups which are introduced with high stereo and regioselectivity, as well as processes for their obtention.Peer reviewedLaboratorios del Dr. Esteve S.A.A1 Solicitud de patente con informe sobre el estado de la técnic
The synthesis of constrained spirocycles is achieved effectively by means of 1,3-dipolar cyclodditio...
Depuis quelques années, l’élaboration de molécules spiraniques connait un essor considérable avec, e...
18 pagesStudies dealing with the diastereoselective installation of 9 stereogenic centers of the C12...
The invention provides highly functionalised spiro-fused azetidinones of formula I: having a cyclohe...
The invention provides highly functionalised spiro-fused aZetidinones having a cycloheXane moiety W...
The invention provides highly functionalised spiro-fused lac tams of en formula (I) having a cycloh...
New spirolactams of formula (I) having a benzodienone moiety and a azetidinone moiety which are high...
The invention provides highly functionalised spiro-fused lactams of formula (1) having a cyclohexane...
The present invention refers to a process for rearranging a spirolactam (I) under acidic conditions ...
International audienceThis work describes a modular efficient route to 10-aza-4-thia-, 10-aza-4-oxa-...
Après avoir exposé les enjeux de ce travail en présentant dans le chapitre 1 les produits naturels p...
Les travaux décrits dans ce manuscrit de thèse ont porté d'une part sur le développement de nouvelle...
The enantioselective total synthesis of spirofungins A (1) and B (2) is reported in 14 steps over th...
Alkaloids from the family of the tetrahydroisoquinolins exhibit powerful antitumor and antibiotic ac...
International audiencePolycyclic structures fused at a central carbon are of great interest due to t...
The synthesis of constrained spirocycles is achieved effectively by means of 1,3-dipolar cyclodditio...
Depuis quelques années, l’élaboration de molécules spiraniques connait un essor considérable avec, e...
18 pagesStudies dealing with the diastereoselective installation of 9 stereogenic centers of the C12...
The invention provides highly functionalised spiro-fused azetidinones of formula I: having a cyclohe...
The invention provides highly functionalised spiro-fused aZetidinones having a cycloheXane moiety W...
The invention provides highly functionalised spiro-fused lac tams of en formula (I) having a cycloh...
New spirolactams of formula (I) having a benzodienone moiety and a azetidinone moiety which are high...
The invention provides highly functionalised spiro-fused lactams of formula (1) having a cyclohexane...
The present invention refers to a process for rearranging a spirolactam (I) under acidic conditions ...
International audienceThis work describes a modular efficient route to 10-aza-4-thia-, 10-aza-4-oxa-...
Après avoir exposé les enjeux de ce travail en présentant dans le chapitre 1 les produits naturels p...
Les travaux décrits dans ce manuscrit de thèse ont porté d'une part sur le développement de nouvelle...
The enantioselective total synthesis of spirofungins A (1) and B (2) is reported in 14 steps over th...
Alkaloids from the family of the tetrahydroisoquinolins exhibit powerful antitumor and antibiotic ac...
International audiencePolycyclic structures fused at a central carbon are of great interest due to t...
The synthesis of constrained spirocycles is achieved effectively by means of 1,3-dipolar cyclodditio...
Depuis quelques années, l’élaboration de molécules spiraniques connait un essor considérable avec, e...
18 pagesStudies dealing with the diastereoselective installation of 9 stereogenic centers of the C12...