Cellular signalling pathways are fundamental to the control and regulation of cell behaviour. Understanding the biosignalling network functions are crucial for studying di erent diseases and for designing e ective therapeutic approaches to them. In this paper we present P systems as a feasible computational modelling tool for cellular signalling pathways that takes into consideration the inherent randomness occurring in biological phenomena and the discrete character of the components of the system. We illustrate these cellular models simulating the EGFR signalling cascade and the FAS{induced apoptosis using a deterministic strategy for evolution of P systems.Ministerio de Educación y Ciencia TIN2005-09345-C04-0
In this paper we present P systems as a reliable computa- tional modelling tool for Systems Biology...
Cell Signaling Networks(CSN) are complex bio-chemical networks which, through evolution, have become...
Today, we can avail of comprehensive information on the molecular mechanisms of apoptosis signaling...
Abstract. Cellular signalling pathways are fundamental to the control and regulation of cell behavio...
Cellular signalling pathways are fundamental to the control and regulation of cell behavior. Unders...
Abstract. Cellular signalling pathways are fundamental to the control and regulation of cell behavio...
In contrast to differential equations, P systems are an unconven- tional model of computation which...
Cells rely on a system of signal processing and transmission networks to perform and coordinate thei...
We have trained a computer model of a simple cell-signaling pathway to give specified responses to a...
Cellular signaling circuits handle an enormous range of computations. Beyond the housekeeping, repli...
In the last few decades, extensive computational studies have been conducted on signaling pathways w...
Abstract: Computer modeling of molecular signaling cascades can provide useful insight into the unde...
In this paper various molecular chemical interactions are modelled under different computational pa...
In an age where the volume of data regarding biological systems exceeds our 27 ability to analyse it...
his article is a critical review of computational techniques used to model, analyse and simulate sig...
In this paper we present P systems as a reliable computa- tional modelling tool for Systems Biology...
Cell Signaling Networks(CSN) are complex bio-chemical networks which, through evolution, have become...
Today, we can avail of comprehensive information on the molecular mechanisms of apoptosis signaling...
Abstract. Cellular signalling pathways are fundamental to the control and regulation of cell behavio...
Cellular signalling pathways are fundamental to the control and regulation of cell behavior. Unders...
Abstract. Cellular signalling pathways are fundamental to the control and regulation of cell behavio...
In contrast to differential equations, P systems are an unconven- tional model of computation which...
Cells rely on a system of signal processing and transmission networks to perform and coordinate thei...
We have trained a computer model of a simple cell-signaling pathway to give specified responses to a...
Cellular signaling circuits handle an enormous range of computations. Beyond the housekeeping, repli...
In the last few decades, extensive computational studies have been conducted on signaling pathways w...
Abstract: Computer modeling of molecular signaling cascades can provide useful insight into the unde...
In this paper various molecular chemical interactions are modelled under different computational pa...
In an age where the volume of data regarding biological systems exceeds our 27 ability to analyse it...
his article is a critical review of computational techniques used to model, analyse and simulate sig...
In this paper we present P systems as a reliable computa- tional modelling tool for Systems Biology...
Cell Signaling Networks(CSN) are complex bio-chemical networks which, through evolution, have become...
Today, we can avail of comprehensive information on the molecular mechanisms of apoptosis signaling...