Whole-Genome Sequencing Analysis from the Chikungunya Virus Caribbean Outbreak Reveals Novel Evolutionary Genomic Elements
- Stapleford, Kenneth,
- Moratorio, Gonzalo
- Henningsson, Rasmus
- Chen, Rubing
- Matheus, Severine
- Enfissi, Antoine
- Weissglas-Volkov, Daphna
- Isakov, Ofer
- Blanc, Hervé
- Mounce, Bryan C.
- Dupont-Rouzeyrol, Myrielle
- Shomron, Noam
- Weaver, Scott
- Fontes, Magnus
- Rousset, Dominique
- Vignuzzi, Marco
Publication date
January 2016
DOI Publisher
Public Library of Science (PLoS)Abstract
International audienceChikungunya virus (CHIKV), an alphavirus and member of the Togaviridae family, is capable of causing severe febrile disease in humans. In December of 2013 the Asian Lineage of CHIKV spread from the Old World to the Americas, spreading rapidly throughout the New World. Given this new emergence in naïve populations we studied the viral genetic diversity present in infected individuals to understand how CHIKV may have evolved during this continuing outbreak
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