Calcitonin was discovered in the early 1960s [1], at which time it was assumed to be a single hormone with a yet-to-be-determined role in human physiology. Since then it has been found to be only one entity among a large array of related circulating peptides, at least one of which has a pivotal role in the host response to microbial infections [2, 3]. The aim of this review is to describe this metamorphosis of an endocrine hormone to a new class of hormokine mediators in infectious diseases
Sepsis is the human body’s response to severe infection. It has been historically challenging to det...
Introduction: Procalcitonin (PCT) is a 13 kD protein with a chain of 116 amino acids. It consists of...
The menace of antibiotic resistance is on the rise, and one critical reason for that is the inapprop...
Septic shock is a leading cause of mortality in intensive care units, but can be difficult to distin...
Immunoneutralization of procalcitonin (ProCT), a putative mediator of sepsis, has been shown to incr...
Despite advances in the diagnosis and treatment of infections diseases, sepsis and ensuing multiorga...
Used appropriately, biomarkers improve the assessment of respiratory tract infections and sepsis. Mo...
Although it has not always been known as the same name, the clinical presentation and implications o...
In contrast to calcitonin which is primarily synthesized in the thyroid, procalcitonin is a prohormo...
In contrast to Calcitonin that is primarily synthesized in the thyroid, Procalcitonin is the prohorm...
Calcitonin precursors (CTpr), including procalcitonin, are important markers and also potentially ha...
Over the last 25 years, procalcitonin (PCT) has increasingly been utilized to identify patients with...
An ideal marker for bacterial infections should allow an early diagnosis, inform about the course an...
Procalcitonin (PCT) is a precursor peptide for the hormone calcitonin and is frequently increased in...
SUMMARY, Procalcitonin is a 14-kDa protein encoded by the Calc-I gene along with calcitonin and kata...
Sepsis is the human body’s response to severe infection. It has been historically challenging to det...
Introduction: Procalcitonin (PCT) is a 13 kD protein with a chain of 116 amino acids. It consists of...
The menace of antibiotic resistance is on the rise, and one critical reason for that is the inapprop...
Septic shock is a leading cause of mortality in intensive care units, but can be difficult to distin...
Immunoneutralization of procalcitonin (ProCT), a putative mediator of sepsis, has been shown to incr...
Despite advances in the diagnosis and treatment of infections diseases, sepsis and ensuing multiorga...
Used appropriately, biomarkers improve the assessment of respiratory tract infections and sepsis. Mo...
Although it has not always been known as the same name, the clinical presentation and implications o...
In contrast to calcitonin which is primarily synthesized in the thyroid, procalcitonin is a prohormo...
In contrast to Calcitonin that is primarily synthesized in the thyroid, Procalcitonin is the prohorm...
Calcitonin precursors (CTpr), including procalcitonin, are important markers and also potentially ha...
Over the last 25 years, procalcitonin (PCT) has increasingly been utilized to identify patients with...
An ideal marker for bacterial infections should allow an early diagnosis, inform about the course an...
Procalcitonin (PCT) is a precursor peptide for the hormone calcitonin and is frequently increased in...
SUMMARY, Procalcitonin is a 14-kDa protein encoded by the Calc-I gene along with calcitonin and kata...
Sepsis is the human body’s response to severe infection. It has been historically challenging to det...
Introduction: Procalcitonin (PCT) is a 13 kD protein with a chain of 116 amino acids. It consists of...
The menace of antibiotic resistance is on the rise, and one critical reason for that is the inapprop...