Toksisitas Dan Karakterisasi Gugus Fungsi Daun Sisik Naga (Drymoglossum Piloselloides (L) Presl.)

The purpose of this study was to determine LC50 sisik naga (Drymoglossum piloselloides (L) Presl) epiphytic leaf extract using Brine Shrimp Lethality Test (BSLT), and to know the characteristics of functional groups contained in the extract of the most toxic fraction. The method used in this study was Maceration and fractionation. The implementation of toxicity test used BSLT method. The toxicity test was then performed the isolation of compounds by thin layer chromatography (TLC), and then determined the characteristics of functional groups with spectrophotometer Fourier Transform Infra Red (FTIR). The result showed that the most toxic fraction has LC50 values ​​of 15.71 ppm which has the potential as anti-cancer. The result of the isolation of the most toxic fraction obtains at least seven compounds, then identified by FTIR spectrophotometer suspected this fraction contains amine functional groups and amide (N-H), phenol, alcohol monomers, alcohol hydrogen bonds (O-H), alkanes, alkenes (C-H), aldehyde, ketone, carboxylic acid, ester (C=O), alcohol, ether, carboxylic acid and ester (C-O)