Add to ORKGInternational audienceIt has been suggested in the literature that a disorganization of cardiac tissue at the cellular scale may affect the propagation of the action potential (AP) at the tissue scale, and may play a role in arrhythmia. We developed a model of the myocardium at sub-cellular resolution in which the intracellular space, the cell membrane, and the extracellular space are discretized individually. We tested this approach on small, hand-crafted two- and three-dimensional networks of cells
In this paper we introduce our findings which can lead to a mathematical method for simplifying cell...
Computational models of the heart, from cell-level models, through one-, two- and three-dimensional ...
In mammalian hearts, initiation of the heartbeat occurs in a region of specialised pacemaker cells k...
International audienceIt has been suggested in the literature that a disorganization of cardiac tiss...
International audienceIt has been suggested in the literature that a disorgani-sation of cardiac tis...
During the last decades, studies regarding the prospective impact of the alterations at the microsco...
Dans les dernières décennies, l'impact dû à l'altération de la microstructure du tissu cardiaque dan...
Heterogeneous repolarization causes dispersion of the T-wave and has been linked to arrhythmogenesis...
In this paper, we study a mathematical model of cardiac tissue based on explicit representation of i...
The development of mathematical models of the heart has been an ongoing concern for many decades. Th...
The goal of this thesis is to develop a biophysically and geometrically accurate discrete-cell compu...
Each normal cardiac cycle is started by an action potential that is initiated in the sino-atrial (SA...
Computer modeling has played a unique role in understanding electrocardiography. Modeling and simula...
In this paper, we formulate a model for human ventricular cells that is efficient enough for whole o...
Computational models of the heart at multiple spatial scales, from sub-cellular nanodomains to the w...
In this paper we introduce our findings which can lead to a mathematical method for simplifying cell...
Computational models of the heart, from cell-level models, through one-, two- and three-dimensional ...
In mammalian hearts, initiation of the heartbeat occurs in a region of specialised pacemaker cells k...
International audienceIt has been suggested in the literature that a disorganization of cardiac tiss...
International audienceIt has been suggested in the literature that a disorgani-sation of cardiac tis...
During the last decades, studies regarding the prospective impact of the alterations at the microsco...
Dans les dernières décennies, l'impact dû à l'altération de la microstructure du tissu cardiaque dan...
Heterogeneous repolarization causes dispersion of the T-wave and has been linked to arrhythmogenesis...
In this paper, we study a mathematical model of cardiac tissue based on explicit representation of i...
The development of mathematical models of the heart has been an ongoing concern for many decades. Th...
The goal of this thesis is to develop a biophysically and geometrically accurate discrete-cell compu...
Each normal cardiac cycle is started by an action potential that is initiated in the sino-atrial (SA...
Computer modeling has played a unique role in understanding electrocardiography. Modeling and simula...
In this paper, we formulate a model for human ventricular cells that is efficient enough for whole o...
Computational models of the heart at multiple spatial scales, from sub-cellular nanodomains to the w...
In this paper we introduce our findings which can lead to a mathematical method for simplifying cell...
Computational models of the heart, from cell-level models, through one-, two- and three-dimensional ...
In mammalian hearts, initiation of the heartbeat occurs in a region of specialised pacemaker cells k...