Structural peculiarities of ter-polymeric carboxylic ion-exchanger designed for sorption of proteins.

Carboxylic cation-exchanger K-120 has been developed for sorption of proteins. It has aliphatic matrix containing methacrylic and acrylic acid units and thermodynamically flexible crosslinking agent. The introduction of acrylic acid units together with methacrylic changes the ionization parameters of cation-exchanger and enhances essentially sorption ability towards proteins. The defined level of functional groups ionization provides high binding capacity and reversibility. Enhanced content of cross-linking agent ensures appropriate osmotic stability of the network. Spherical polymeric beads are permeable for protein molecules. Scanning electron microscopy testifies about micro globular structure of synthesized carboxylic ion-exchanger