Until recently, little light had been shed on the murky origins of human malaria. Did Plasmodium falciparum, the most virulent malaria parasite, emerge as a common pathogen only in the past few thousand years, as suggested by some analyses of its nucleotide sequence diversity? Or, was it an ancient scourge of early humans <100 000 years ago, as suggested by others? A recent study, using complete mitochondrial DNA sequence polymorphism data and new analytical methods, points to an intermediate date of origin and expansion out of Africa. Subsequent population growth in each continent is less well resolved
DNA sequence data reveal extensive polymorphism in the virulent, human malaria parasite Plasmodium f...
Plasmodium falciparum, the causative agent of malignant malaria, is among the most severe human infe...
Malaria has troubled humans for thousands of years. Disease resembling malaria has been described fo...
The emergence of virulent Plasmodium falciparum in Africa within the past 6000 years as a result of ...
The origin and geographical spread of Plasmodium falciparum is here determined by analysis of mitoch...
The origin and geographical spread of Plasmodium falciparum is here determined by analysis of mitoch...
We have analyzed DNA sequences from world-wide geographic strains of Plasmodium falciparum and found...
Financial support was provided by The Wellcome Trust (grant ref. 055487), the European Commission, ...
Plasmodium vivax (Pv) malaria is a human infecting blood parasite distributed widely across both tro...
Malaria remains one of the most significant global public health burdens, with nearly half of the wo...
Plasmodium vivax, the second most prevalent of the human malaria parasites, is estimated to affect 7...
Phylogenetic analysis of Plasmodium parasites has indicated that their modern-day distribution is a ...
Abstract. Although the geographic origin of malaria cases imported into the United States can often ...
Abstract Background Timing the origin of human malarias has been a focus of great interest. Previous...
The ability to identify mixed-species infections and track the origin of Plasmodium parasites can fu...
DNA sequence data reveal extensive polymorphism in the virulent, human malaria parasite Plasmodium f...
Plasmodium falciparum, the causative agent of malignant malaria, is among the most severe human infe...
Malaria has troubled humans for thousands of years. Disease resembling malaria has been described fo...
The emergence of virulent Plasmodium falciparum in Africa within the past 6000 years as a result of ...
The origin and geographical spread of Plasmodium falciparum is here determined by analysis of mitoch...
The origin and geographical spread of Plasmodium falciparum is here determined by analysis of mitoch...
We have analyzed DNA sequences from world-wide geographic strains of Plasmodium falciparum and found...
Financial support was provided by The Wellcome Trust (grant ref. 055487), the European Commission, ...
Plasmodium vivax (Pv) malaria is a human infecting blood parasite distributed widely across both tro...
Malaria remains one of the most significant global public health burdens, with nearly half of the wo...
Plasmodium vivax, the second most prevalent of the human malaria parasites, is estimated to affect 7...
Phylogenetic analysis of Plasmodium parasites has indicated that their modern-day distribution is a ...
Abstract. Although the geographic origin of malaria cases imported into the United States can often ...
Abstract Background Timing the origin of human malarias has been a focus of great interest. Previous...
The ability to identify mixed-species infections and track the origin of Plasmodium parasites can fu...
DNA sequence data reveal extensive polymorphism in the virulent, human malaria parasite Plasmodium f...
Plasmodium falciparum, the causative agent of malignant malaria, is among the most severe human infe...
Malaria has troubled humans for thousands of years. Disease resembling malaria has been described fo...