We argue that the large-dimensional dynamical systems which frequently occur in biological models can sometimes be effectively reduced to much smaller ones. We illustrate this by applying projection operator techniques to a mean-field model of an infectious disease spreading through a population of households. In this way, we are able to accurately approximate the dynamics of the system in terms of a few key quantities greatly reducing the number of equations required. We investigate linear stability in this framework and find a new way of calculating the familiar threshold criterion for household systems
We describe a discrete event simulation model of tuberculosis (TB) and HIV disease, parameterized to...
Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneo...
Policies regarding the use of the Bacille Calmette-Guérin (BCG) vaccine for tuberculosis vary greatl...
OBJECTIVE: To investigate the factors influencing the performance and cost-efficacy of periodic roun...
BACKGROUND: Many models used in theoretical ecology, or mathematical epidemiology are stochastic, an...
Current control methods for Tuberculosis (TB) disease have failed to keep pace with the TB epidemics...
Human immunodeficiency virus (HIV) increases the risks of developing tuberculosis (TB) disease follo...
Continuous differential equations are often applied to small populations with little time spent on u...
To investigate the factors influencing the performance and cost-efficacy of periodic rounds of activ...
Human immunodeficiency virus (HIV) increases the risks of developing tuberculosis (TB) disease follo...
BACKGROUND: It has been suggested that a new strategy for HIV prevention, 'Universal Test and Treat'...
In public health programmes interventions are frequently combined with hoped for 'synergies'[22]. Ho...
Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneo...
The mathematical modelling of disease dynamics is now well-established, which allows us to better un...
Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneo...
We describe a discrete event simulation model of tuberculosis (TB) and HIV disease, parameterized to...
Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneo...
Policies regarding the use of the Bacille Calmette-Guérin (BCG) vaccine for tuberculosis vary greatl...
OBJECTIVE: To investigate the factors influencing the performance and cost-efficacy of periodic roun...
BACKGROUND: Many models used in theoretical ecology, or mathematical epidemiology are stochastic, an...
Current control methods for Tuberculosis (TB) disease have failed to keep pace with the TB epidemics...
Human immunodeficiency virus (HIV) increases the risks of developing tuberculosis (TB) disease follo...
Continuous differential equations are often applied to small populations with little time spent on u...
To investigate the factors influencing the performance and cost-efficacy of periodic rounds of activ...
Human immunodeficiency virus (HIV) increases the risks of developing tuberculosis (TB) disease follo...
BACKGROUND: It has been suggested that a new strategy for HIV prevention, 'Universal Test and Treat'...
In public health programmes interventions are frequently combined with hoped for 'synergies'[22]. Ho...
Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneo...
The mathematical modelling of disease dynamics is now well-established, which allows us to better un...
Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneo...
We describe a discrete event simulation model of tuberculosis (TB) and HIV disease, parameterized to...
Early mathematical representations of infectious disease dynamics assumed a single, large, homogeneo...
Policies regarding the use of the Bacille Calmette-Guérin (BCG) vaccine for tuberculosis vary greatl...