peer reviewedDual-specificity phosphatase 3 (DUSP3) is a small phosphatase with poorly known physiological functions and for which only a few substrates are known. Using DUSP3-deficient mice, we recently reported that DUSP3 deficiency confers resistance to endotoxin- and polymicrobial-induced septic shock. We showed that this protection was macrophage dependent. In this study, we further investigated the role of DUSP3 in sepsis tolerance and showed that the resistance is sex dependent. Using adoptive-transfer experiments and ovariectomized mice, we highlighted the role of female sex hormones in the phenotype. Indeed, in ovariectomized female and male mice, the dominance of M2-like macrophages observed in DUSP32/2 female mice was reduced, ...
Background-A limitation of current antiplatelet therapies is their inability to separate thrombotic ...
Dual-specificity phosphatase (DUSP) 1 dephosphorylates and inactivates members of the MAPK superfami...
Poxviruses encode a large variety of proteins that mimic, block or enhance host cell signaling pathw...
Dual-specificity phosphatase 3 (DUSP3) is a small phosphatase with poorly known physiological functi...
We report the generation of dual-specificity phosphatase 3 (DUSP3) deficient mice. These mice develo...
DUSP3 is a small dual-specificity protein phosphatase with an unknown physiological function. We rep...
peer reviewedVaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important ro...
Dual-specificity phosphatase (DUSP) 1 dephosphorylates and inactivates members of the MAPK superfami...
DUSP3, also called Vaccinia-H1 Related (VHR) is a small dual specificity phosphatase dephosphorylati...
The role of dual specificity phosphatase 1 (DUSP1) in inducible nitric oxide synthase (iNOS) express...
THE ROLE OF DUAL SPECIFICITY PHOSPHATASE -11 IN INNATE AND ADAPTIVE IMMUNE RESPONSES Kalyan Chakrava...
<div><p>The mitogen-activated protein kinase (MAPK) pathway regulates many key cellular processes su...
Abstract Endotoxic shock (ExSh) and cecal ligature and puncture (CLP) are models that induce sepsis....
BACKGROUND AND AIMS: Dual Specificity Phosphatase 3 (DUSP3) is a positive regulator of the innate i...
Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cy...
Background-A limitation of current antiplatelet therapies is their inability to separate thrombotic ...
Dual-specificity phosphatase (DUSP) 1 dephosphorylates and inactivates members of the MAPK superfami...
Poxviruses encode a large variety of proteins that mimic, block or enhance host cell signaling pathw...
Dual-specificity phosphatase 3 (DUSP3) is a small phosphatase with poorly known physiological functi...
We report the generation of dual-specificity phosphatase 3 (DUSP3) deficient mice. These mice develo...
DUSP3 is a small dual-specificity protein phosphatase with an unknown physiological function. We rep...
peer reviewedVaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important ro...
Dual-specificity phosphatase (DUSP) 1 dephosphorylates and inactivates members of the MAPK superfami...
DUSP3, also called Vaccinia-H1 Related (VHR) is a small dual specificity phosphatase dephosphorylati...
The role of dual specificity phosphatase 1 (DUSP1) in inducible nitric oxide synthase (iNOS) express...
THE ROLE OF DUAL SPECIFICITY PHOSPHATASE -11 IN INNATE AND ADAPTIVE IMMUNE RESPONSES Kalyan Chakrava...
<div><p>The mitogen-activated protein kinase (MAPK) pathway regulates many key cellular processes su...
Abstract Endotoxic shock (ExSh) and cecal ligature and puncture (CLP) are models that induce sepsis....
BACKGROUND AND AIMS: Dual Specificity Phosphatase 3 (DUSP3) is a positive regulator of the innate i...
Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cy...
Background-A limitation of current antiplatelet therapies is their inability to separate thrombotic ...
Dual-specificity phosphatase (DUSP) 1 dephosphorylates and inactivates members of the MAPK superfami...
Poxviruses encode a large variety of proteins that mimic, block or enhance host cell signaling pathw...