Add to ORKGBACKGROUND Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flexion contractures. We hypothesized that multiple genetic and environmental factors influence susceptibility to this disease and sought to identify susceptibility genes to better understand its pathogenesis. METHODS We conducted a genomewide association study of 960 Dutch persons with Dupuytren's disease and 3117 controls (the discovery set) to test for association between the disease and genetic markers. We tested the 35 single-nucleotide polymorphisms (SNPs) most strongly associated with Dupuytren's disease (P< 1x10-4) in the discovery set in three additional, independent case series comprising a total of 1365 affected persons and 8445 control...
Genetic background plays an important role in the development of Dupuytren's disease. A genome-wide ...
Individuals with Dupuytren’s disease (DD) are commonly seen by physicians and surgeons across multip...
A role of Wnt signaling in Dupuytren disease, a fibroproliferative disease of the hand and fingers, ...
BACKGROUND Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flexi...
BACKGROUND Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flex...
BACKGROUND: Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to ...
Objective: Dupuytren’s disease is a progressive fibrosis of the hand that often results in debilitat...
Dupuytren's disease, a fibromatosis of the connective tissue in the palm, is a common complex diseas...
Dupuytren´s disease, a fibromatosis of the connective tissue in the palm, is a common complex diseas...
Dupuytren´s disease, a fibromatosis of the connective tissue in the palm, is a common complex ...
<div><p>Dupuytren´s disease, a fibromatosis of the connective tissue in the palm, is a common comple...
Individuals with Dupuytren disease (DD) are commonly seen by physicians and surgeons across multiple...
Genetic background plays an important role in the development of Dupuytren's disease. A genome-wide ...
Individuals with Dupuytren’s disease (DD) are commonly seen by physicians and surgeons across multip...
A role of Wnt signaling in Dupuytren disease, a fibroproliferative disease of the hand and fingers, ...
BACKGROUND Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flexi...
BACKGROUND Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flex...
BACKGROUND: Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to ...
Objective: Dupuytren’s disease is a progressive fibrosis of the hand that often results in debilitat...
Dupuytren's disease, a fibromatosis of the connective tissue in the palm, is a common complex diseas...
Dupuytren´s disease, a fibromatosis of the connective tissue in the palm, is a common complex diseas...
Dupuytren´s disease, a fibromatosis of the connective tissue in the palm, is a common complex ...
<div><p>Dupuytren´s disease, a fibromatosis of the connective tissue in the palm, is a common comple...
Individuals with Dupuytren disease (DD) are commonly seen by physicians and surgeons across multiple...
Genetic background plays an important role in the development of Dupuytren's disease. A genome-wide ...
Individuals with Dupuytren’s disease (DD) are commonly seen by physicians and surgeons across multip...
A role of Wnt signaling in Dupuytren disease, a fibroproliferative disease of the hand and fingers, ...