The work presented in this thesis was aimed at characterizing cationic liposome-mediated transfection and, more specifically, investigated the properties of the synthetic cationic lipid SAINT-2. In this final chapter, the data obtained with SAINT-2 containing liposomes will be summarized and discussed. Some perspective concerning the future application of cationic liposomes in different gene therapy approaches will also be presented. Zie: Summary.
Gene therapy is an active field that has progressed rapidly into clinical trials in a relatively sho...
Cationic liposome-DNA complexes, also called lipoplexes , constitute a potentially viable alternati...
Despite extensive research in the last decade on the use of cationic liposomes as gene transfer vect...
The use of an efficient carrier for nucleic acid-based medicines is considered to be a determinant f...
Great expectations from the application of gene therapy approaches to human disease have been impair...
Cationic liposome-DNA complexes (lipoplexes) constitute a potentially viable alternative to viral ve...
After a decade of clinical trials, gene therapy seems to have found its place between excessive ambi...
Objectives. Gene therapy is based on the introduction of genetic material into cells, tissues, or or...
International audienceOver the last several years, various gene delivery systems have been developed...
Recent rapid developments in genomics will likely lead to a rapid expansion in identifying defective...
Abstract. Cationic liposomes, consisting of synthetic amphiphiles and a socalled helper lipid, rapid...
Abstract: Cationic liposomes (CLs) are used as gene vectors (carriers) in worldwide human clinical t...
Cationic liposomes have been widely used as a transfection reagent to introduce gene into cells. Alt...
Gene therapy is an active field that has progressed rapidly into clinical trials in a relatively sho...
Cationic liposome-DNA complexes, also called lipoplexes , constitute a potentially viable alternati...
Despite extensive research in the last decade on the use of cationic liposomes as gene transfer vect...
The use of an efficient carrier for nucleic acid-based medicines is considered to be a determinant f...
Great expectations from the application of gene therapy approaches to human disease have been impair...
Cationic liposome-DNA complexes (lipoplexes) constitute a potentially viable alternative to viral ve...
After a decade of clinical trials, gene therapy seems to have found its place between excessive ambi...
Objectives. Gene therapy is based on the introduction of genetic material into cells, tissues, or or...
International audienceOver the last several years, various gene delivery systems have been developed...
Recent rapid developments in genomics will likely lead to a rapid expansion in identifying defective...
Abstract. Cationic liposomes, consisting of synthetic amphiphiles and a socalled helper lipid, rapid...
Abstract: Cationic liposomes (CLs) are used as gene vectors (carriers) in worldwide human clinical t...
Cationic liposomes have been widely used as a transfection reagent to introduce gene into cells. Alt...
Gene therapy is an active field that has progressed rapidly into clinical trials in a relatively sho...
Cationic liposome-DNA complexes, also called lipoplexes , constitute a potentially viable alternati...
Despite extensive research in the last decade on the use of cationic liposomes as gene transfer vect...