Functional polymorphisms in receptors for IgG (FcyR), affecting IgG binding, were first described in 1983, when a clear non-responder population was identified in the mitogenic effect on T cells of mouse IgG1 anti-CD3 antibodies (1). In the following years, our knowledge of structural diversity and heterogeneity in FcyR increased substantially, and clinical consequences of this variety became apparent (2,3). With the development of single and multiple Fc receptor deficient mice in the past decade, our view on Fc receptor interactions in the inflammatory response changed markedly (4, Chapter 1). More recent findings force us to revise our view on the involvement of FcyR polymorphisms in this response as well (Chapter 9). Zie: Summary
Fcγ receptors (FcγRs) are key immune receptors responsible for the effective control of both humoral...
In this thesis the role of murine FcgammaR in autoimmune diseases is analyzed with special focus on...
Receptors for the Fc domains of IgG (Fc \u3b3 R) play a critical role in linking humoral and cellula...
were first described in 1983, when a clear non-responder population was identified in the mitogenic ...
International audienceImpressive advances in defining the properties of receptors for the Fc portion...
Receptors for immunoglobulins (Fc receptors) play a central role during an immune response, as they ...
During the past decade, our knowledge of Fc receptor interactions in inflammation has increased dram...
During the past decade, our knowledge of Fc receptor interactions in inflammation has increased dram...
International audienceThe biological activities of human IgG antibodies predominantly rely on a fami...
AbstractHuman autoimmune diseases thought to arise from the combined effects of multiple susceptibil...
The known IgG FcRs primarily mediate inflammation by interacting with IgG1, even though IgG2 isotype...
Fc gamma receptors (FcγRs) are receptors for immunoglobulin G (IgG), the most abundant of five class...
Both non-immune “natural” and antigen-induced “immune” IgM are important for protection against path...
Circulating immune complexes play an important role in the modulation of antibody responses and in t...
International audienceImmunoglobulin G (IgG) is the predominant antibody class generated during infe...
Fcγ receptors (FcγRs) are key immune receptors responsible for the effective control of both humoral...
In this thesis the role of murine FcgammaR in autoimmune diseases is analyzed with special focus on...
Receptors for the Fc domains of IgG (Fc \u3b3 R) play a critical role in linking humoral and cellula...
were first described in 1983, when a clear non-responder population was identified in the mitogenic ...
International audienceImpressive advances in defining the properties of receptors for the Fc portion...
Receptors for immunoglobulins (Fc receptors) play a central role during an immune response, as they ...
During the past decade, our knowledge of Fc receptor interactions in inflammation has increased dram...
During the past decade, our knowledge of Fc receptor interactions in inflammation has increased dram...
International audienceThe biological activities of human IgG antibodies predominantly rely on a fami...
AbstractHuman autoimmune diseases thought to arise from the combined effects of multiple susceptibil...
The known IgG FcRs primarily mediate inflammation by interacting with IgG1, even though IgG2 isotype...
Fc gamma receptors (FcγRs) are receptors for immunoglobulin G (IgG), the most abundant of five class...
Both non-immune “natural” and antigen-induced “immune” IgM are important for protection against path...
Circulating immune complexes play an important role in the modulation of antibody responses and in t...
International audienceImmunoglobulin G (IgG) is the predominant antibody class generated during infe...
Fcγ receptors (FcγRs) are key immune receptors responsible for the effective control of both humoral...
In this thesis the role of murine FcgammaR in autoimmune diseases is analyzed with special focus on...
Receptors for the Fc domains of IgG (Fc \u3b3 R) play a critical role in linking humoral and cellula...