Add to ORKGThe main objective of the research described in the present thesis was to increase our understanding concerning the functional relationship between cellular sphingolipids and the regulation of processes such as cell differentiation, apoptosis and multidrug resistance (MDR). The general approach we employed was to modulate the sphingolipid metabolism of cultured cells by pharmacological- and biochemical means, and to study the subsequent effects of these treatments on various cell physiological phenomena. .. Zie: Summary
Sphingolipids function as bioactive mediators of different cellular processes, mostly proliferation,...
Bioactive sphingolipids, including ceramide, sphingosine and sphingosine 1-phosphate are important r...
AbstractThrough modifications in the fine membrane structure, cell–cell or cell–matrix interactions,...
Sphingolipids are important components of the cell involved in the processes of apoptosis, inflammat...
Sphingolipids are important components of the cell involved in the processes of apoptosis, inflammat...
Abstract: It has been widely shown that ceramide, ceramide phosphate, sphingosine and sphingosine-1-...
The main goal of the research described in this thesis was to obtain more insight into the potential...
Drug resistance elicited by cancer cells still constitutes a huge problem that frequently impairs th...
AbstractSphingolipids are known to play important roles in the regulation of cell proliferation, res...
Sphingolipids are major constituents of the cells with emerging roles in the regulation of cellular ...
Introduction: Sphingolipids represent a diverse class of lipid molecules. In addition to their funct...
Sphingolipids. A significant corpus of work over the last decade has firmly established an important...
Sphingolipids are ubiquitous in eukaryotic cells where they have been attributed a plethora of funct...
Sphingolipids have emerged as molecules whose metabolism is regulated leading to generation of bioac...
Sphingolipids not only function as structural components of cell membranes but also act as signaling...
Sphingolipids function as bioactive mediators of different cellular processes, mostly proliferation,...
Bioactive sphingolipids, including ceramide, sphingosine and sphingosine 1-phosphate are important r...
AbstractThrough modifications in the fine membrane structure, cell–cell or cell–matrix interactions,...
Sphingolipids are important components of the cell involved in the processes of apoptosis, inflammat...
Sphingolipids are important components of the cell involved in the processes of apoptosis, inflammat...
Abstract: It has been widely shown that ceramide, ceramide phosphate, sphingosine and sphingosine-1-...
The main goal of the research described in this thesis was to obtain more insight into the potential...
Drug resistance elicited by cancer cells still constitutes a huge problem that frequently impairs th...
AbstractSphingolipids are known to play important roles in the regulation of cell proliferation, res...
Sphingolipids are major constituents of the cells with emerging roles in the regulation of cellular ...
Introduction: Sphingolipids represent a diverse class of lipid molecules. In addition to their funct...
Sphingolipids. A significant corpus of work over the last decade has firmly established an important...
Sphingolipids are ubiquitous in eukaryotic cells where they have been attributed a plethora of funct...
Sphingolipids have emerged as molecules whose metabolism is regulated leading to generation of bioac...
Sphingolipids not only function as structural components of cell membranes but also act as signaling...
Sphingolipids function as bioactive mediators of different cellular processes, mostly proliferation,...
Bioactive sphingolipids, including ceramide, sphingosine and sphingosine 1-phosphate are important r...
AbstractThrough modifications in the fine membrane structure, cell–cell or cell–matrix interactions,...