Biofilm formation on surface modified silicone rubber voice prostheses

Total laryngectomy is a surgical treatment for extensive cancer of the larynx or hypopharynx, which alters speech, swallowing, and respiration. During the last two decades, surgical voice restoration procedures comprising tracheo-esophageal puncture techniques with insertionof a so-called "voiceprosthesis" have greatly improved successful voice acquisition following laryngectomy (see Chapter 1 for a literature survey). ... Zie: Summary