How to fit the treatment to the breast cancer patient

In this thesis a number of tumor and patient characteristics, treatment options with emphasis on chemotherapy and several aspects of quality of life and long term toxicities are discussed. The optimization of standard adjuvant CMF (cyclophosphamide, methotrexate and 5-fluorouracil) with help of a growth factor is described, but the main part of the thesis concerns the experience woth high dose chemotherapy in combination with ABMT and/or PSCT and growth factors. ... Zie: Summary conclusions and further remarks