Replication and maintenance of plasmids in lactococcus lactis

Whereas the majority of plasmids present in lactic acid bacteria, including those of lactococci, are cryptic, several (industrally) important traits are plasmid-encoded and, therefore, can be lost due to plasmid instability. Since plasmid stability is intrinsically linked to the replication of the plasmid, it is clear that a more detailed knowledge of plasmid replication functions is needed for a better understanding of plasmid instability. ... Zie: Summary and general discussion