Heterospecific transformation in Bacillus subtilis

Bacterial transformation is the genetic modification of bacteria following their exposure to exogenous DNA. Both the study of the absorbtion of DNA molecules by a recipient cell and the intracellular processing of entered DNA, resulting in the expression of its genetic information, is of interest in understanding the communication of the cell with its environment. Particularly, the integration of donor DNA into the recipient chromosome, which is a prerequistite for transforming activity of entered chromosomal DNA, provides as interesting tool for the study of general recombination in vivo at the molecular level. ... Zie: Summary and concluding remarks