Add to ORKGIn this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0437) have been investigated in rats and monkeys after different dosing routes. In addition, some bioanalytical aspects of the drug wre studied in telation to its metabolism. The drug was synthesized at the department of Medicinal Chemistry and it has potential applications in Parkinson's deisease, schizophrenia and glaucoma. Readioactive experiments were carried out using [3H] N-0437 with the label in the propyl side chain. ... Zie: Summary
The metabolism of 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0437) was investigated in ...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
Derivatives of the potent dopamine D2-selective agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxy...
Derivatives of the potent dopamine D2-selective agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxy...
Derivatives of the potent dopamine D2-selective agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxy...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
The metabolism of 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0437) was investigated in ...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
In this thesis the metabolic pathways of the new and very potent D-2 agnist 2-(N-propyl-N-2-thienyle...
Derivatives of the potent dopamine D2-selective agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxy...
Derivatives of the potent dopamine D2-selective agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxy...
Derivatives of the potent dopamine D2-selective agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxy...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
The metabolism of 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0437) was investigated in ...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...
This thesis describes the bioanalysis and pharmacokinetics of the S(-) enantiomer (N-0923) of the se...