Add to ORKGThis paper describes the reversible activation of a mechanosensitive channel via a light-sensitive lipid mimic. For these experiments, the mechanosensitive channel of large conductance (MscL) protein from Lactococcus lactis and Escherichia coli was reconstituted in lipid bilayers composed of 80 mol % 1,2-dioleoyl-sn-glycero-3-phosphocholine and 20 mol % di-(5-{[4-(4-butylphenyl)azo]phenoxy}pentyl)phosphate (4-Azo-5P). Light-induced isomerization of the azobenzene moiety of 4-Azo-5P from trans to cis was used to activate MscL.
MscL is a mechanosensitive channel gated by membrane tension in the lipid bilayer alone. Its structu...
One of the best-studied mechanosensitive channels is the mechanosensitive channel of large conductan...
Droplet interface bilayers (DIBs) provide an exciting new platform for the study of membrane protein...
This paper describes the reversible activation of a mechanosensitive channel via a light-sensitive l...
This protocol details the chemical modification of the mechanosensitive channel of large-conductance...
We have studied the effects of lipid structure on the function of the mechanosensitive channel of la...
The mechanosensitive channel of large conductance MscL from Escherichia coli has been reconstituted ...
mechanosensitive (MS) channels open in response to membrane stretch. The most studied of the MS cha...
<div><p>The mechanosensitive channel of large conductance (MscL) is a protein that responds to membr...
Microbial cells constitutively express the Large Conductance Mechanosensitive Channel which opens in...
Photochemical processes provide versatile triggers of chemical reactions. Here, we use a photoactiva...
AbstractIn this article, we examine the mechanical role of the lipid bilayer in ion channel conforma...
ABSTRACT In this article, we examine the mechanical role of the lipid bilayer in ion channel conform...
Understanding the functioning of ion channels, as well as utilizing their properties for biochemical...
The mechanosensitive channel of large conductance (MscL) is a protein that responds to membrane tens...
MscL is a mechanosensitive channel gated by membrane tension in the lipid bilayer alone. Its structu...
One of the best-studied mechanosensitive channels is the mechanosensitive channel of large conductan...
Droplet interface bilayers (DIBs) provide an exciting new platform for the study of membrane protein...
This paper describes the reversible activation of a mechanosensitive channel via a light-sensitive l...
This protocol details the chemical modification of the mechanosensitive channel of large-conductance...
We have studied the effects of lipid structure on the function of the mechanosensitive channel of la...
The mechanosensitive channel of large conductance MscL from Escherichia coli has been reconstituted ...
mechanosensitive (MS) channels open in response to membrane stretch. The most studied of the MS cha...
<div><p>The mechanosensitive channel of large conductance (MscL) is a protein that responds to membr...
Microbial cells constitutively express the Large Conductance Mechanosensitive Channel which opens in...
Photochemical processes provide versatile triggers of chemical reactions. Here, we use a photoactiva...
AbstractIn this article, we examine the mechanical role of the lipid bilayer in ion channel conforma...
ABSTRACT In this article, we examine the mechanical role of the lipid bilayer in ion channel conform...
Understanding the functioning of ion channels, as well as utilizing their properties for biochemical...
The mechanosensitive channel of large conductance (MscL) is a protein that responds to membrane tens...
MscL is a mechanosensitive channel gated by membrane tension in the lipid bilayer alone. Its structu...
One of the best-studied mechanosensitive channels is the mechanosensitive channel of large conductan...
Droplet interface bilayers (DIBs) provide an exciting new platform for the study of membrane protein...