Add to ORKGReduction reactions are an important area of study in organic synthesis and are used to synthesize a variety of compounds. In particular, the reduction of lactones to their respective lactols or hemiacetals is important for the synthesis of biologically active modified carbohydrates which are often used in drug design. The reduction of the sugar-based lactones to their respective lactols with lithium triethyl borohydride (LiEt3BH) will be the focus of this project. The efficiency of this reagent to reduce sugar lactones to sugar hemiacetals (lactols) will be studied under different reaction parameters to develop an efficient protocol for its uses. The parameters will include temperature, solvent, time and amount of reducing agent for the re...
Regioselective glycosylation of unprotected glycoside substrates has emerged as an attractive strate...
Resorcylic acid lactones (RALs) are a biologically important and structurally interesting class of n...
A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from comme...
Boron trifluoride etherate-lithium aluminum hydride reduction of 12β-hydroxy-14ξ-rosane 16-carboxyli...
Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irr...
Carbohydrates are among the most abundant class of biomolecules with a variety of derivatives. The g...
This thesis describes the synthesis of some novel carbohydrate lactones and their uses as starting m...
Lactone 4 (R = Bn) can be converted into C-glycosyl compounds by reaction with an organometallic rea...
Lactose was readily transformed into thexyldimethylsilyl (3,4-O-isopropylidene-beta-D-galactopyranos...
The project of this thesis is the comparative study of sodium borohydride catalyzed reactions ...
The stereocontrolled synthesis of new sugar derivatives carrying the α,β-unsaturated δ-lactone (bute...
trans-$\beta$-Lactone natural products have a variety of important biological activities. In particu...
Β-Lactones are present in many biologically active natural products; consequently, much attention ha...
This thesis describes the synthesis of 2-C-branched carbohydrate derivatives from ketohexoses and so...
Climate change is a daunting predicament the world has found itself in, leading to an increase in gr...
Regioselective glycosylation of unprotected glycoside substrates has emerged as an attractive strate...
Resorcylic acid lactones (RALs) are a biologically important and structurally interesting class of n...
A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from comme...
Boron trifluoride etherate-lithium aluminum hydride reduction of 12β-hydroxy-14ξ-rosane 16-carboxyli...
Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irr...
Carbohydrates are among the most abundant class of biomolecules with a variety of derivatives. The g...
This thesis describes the synthesis of some novel carbohydrate lactones and their uses as starting m...
Lactone 4 (R = Bn) can be converted into C-glycosyl compounds by reaction with an organometallic rea...
Lactose was readily transformed into thexyldimethylsilyl (3,4-O-isopropylidene-beta-D-galactopyranos...
The project of this thesis is the comparative study of sodium borohydride catalyzed reactions ...
The stereocontrolled synthesis of new sugar derivatives carrying the α,β-unsaturated δ-lactone (bute...
trans-$\beta$-Lactone natural products have a variety of important biological activities. In particu...
Β-Lactones are present in many biologically active natural products; consequently, much attention ha...
This thesis describes the synthesis of 2-C-branched carbohydrate derivatives from ketohexoses and so...
Climate change is a daunting predicament the world has found itself in, leading to an increase in gr...
Regioselective glycosylation of unprotected glycoside substrates has emerged as an attractive strate...
Resorcylic acid lactones (RALs) are a biologically important and structurally interesting class of n...
A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from comme...