The research described in this thesis is divided into two parts. Part I (chapters 1-3) deals with the development of a novel 2-aminotetralin as a mixed dopamine Dl/D2-receptor agonist, whereas part I1 (chapters 4-6) concerns the development of 2-amidotetralins as nonindolic melatonin-receptor agents.
A novel series of melatonin receptor ligands was discovered by opening the cyclic scaffolds of known...
A series of 2-aminotetralins, substituted with a methoxy or a hydroxy group on the 5- or 7-position,...
This work reports the design and synthesis of novel alkylamides, characterized by a dibenzo- [a,d]c...
The research described in this thesis is divided into two parts. Part I (chapters 1-3) deals with th...
A series of unsubstituted and methoxy-substituted 2-amidotetralins (4a-q) was prepared and evaluated...
A new chemical class of potential atypical antypsychotic agents, based on the pharmacological concep...
A new chemical class of potential atypical antypsychotic agents, based on the pharmacological concep...
The main interest of our research group is the medicinal chemisq of agonists and antagonists of the ...
The main interest of our research group is the medicinal chemisq of agonists and antagonists of the ...
The search for melatonin receptor agonists and antagonists specific towards one of the receptor subt...
International audienceMelatonin receptors have been studied for several decades. The low expression ...
IMPORTANCE OF THE FIELD: Increasing clinical evidences suggest that melatonin receptor agonists ...
Introduction: The neurohormone melatonin (N-acetyl-5-methoxytryptamine) regulates circadian rhythms ...
A novel series of melatonin receptor ligands was discovered by opening the cyclic scaffolds of known...
A novel series of melatonin receptor ligands was discovered by opening the cyclic scaffolds of known...
A series of 2-aminotetralins, substituted with a methoxy or a hydroxy group on the 5- or 7-position,...
This work reports the design and synthesis of novel alkylamides, characterized by a dibenzo- [a,d]c...
The research described in this thesis is divided into two parts. Part I (chapters 1-3) deals with th...
A series of unsubstituted and methoxy-substituted 2-amidotetralins (4a-q) was prepared and evaluated...
A new chemical class of potential atypical antypsychotic agents, based on the pharmacological concep...
A new chemical class of potential atypical antypsychotic agents, based on the pharmacological concep...
The main interest of our research group is the medicinal chemisq of agonists and antagonists of the ...
The main interest of our research group is the medicinal chemisq of agonists and antagonists of the ...
The search for melatonin receptor agonists and antagonists specific towards one of the receptor subt...
International audienceMelatonin receptors have been studied for several decades. The low expression ...
IMPORTANCE OF THE FIELD: Increasing clinical evidences suggest that melatonin receptor agonists ...
Introduction: The neurohormone melatonin (N-acetyl-5-methoxytryptamine) regulates circadian rhythms ...
A novel series of melatonin receptor ligands was discovered by opening the cyclic scaffolds of known...
A novel series of melatonin receptor ligands was discovered by opening the cyclic scaffolds of known...
A series of 2-aminotetralins, substituted with a methoxy or a hydroxy group on the 5- or 7-position,...
This work reports the design and synthesis of novel alkylamides, characterized by a dibenzo- [a,d]c...