Depression after myocardial infarction: etiological, prognostic andtherapeutical aspects

Inspired by the influential study by Frasure-Smith et al (Journal of the American Medical Association 1993), in which it was described that depression following myocardial infarction (MI) was associated with a worse cardiac prognosis, many studies have tried to replicate this finding. Most of these studies were able to confirm this observation, however several studies failed to find an association between post-MI depression and impaired cardiovascular prognosis. Nevertheless, depression is considered to be an independent risk factor for post-MI prognosis. ... Zie: Summary