Asymmetric allylation of aryl aldehydes: studies on the scope and mechanism of the palladium catalysed diethylzinc mediated umpolung using phosphoramidite ligands

Using modular, monodentate phosphoramidite ligands, enantioselective palladium catalysed diethylzinc mediated allylation of aldehydes was achieved. The scope of the asymmetric C–C bond formation was investigated with respect to nucleophilic and electrophilic components and an alternative reaction mechanism is proposed based on our findings.