A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]- octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64.Michelle T. Ma, John A. Karas, Jonathan M. White, Denis Scanlon and Paul S. Donnell
Because of an indisputable pharmacological advatages of radiometal-labeled compounds, a purpose of t...
International audienceWe present here the synthesis of two new bifunctionalized azachelators, no2th-...
A bifunctional chelator for stably complexing metal radionuclides to tumor-targeting molecules is cr...
Publication Date (Web): June 13, 2011The synthesis of new cage amine macrobicyclic ligands with pend...
C1 - Journal Articles RefereedThe synthesis of new cage amine macrobicyclic ligands with pendent car...
A range of new carboxylate functionalised bis(thiosemicarbazone) ligands and their Cu(II) complexes ...
New bifunctional derivatives of diacetyl-bis(4-methylthiosemicarbazone) (H(2)atsm) have been prepare...
The use of copper radioisotopes in cancer diagnosis and radionuclide therapy is possible using chela...
A new class of multifunctionalized sarcophagine derivatives was synthesized for 64Cu chelation. The ...
International audienceAbstract Three new bifunctional copper chelators based on the 1,4,7-triazacycl...
Molecules containing lysine-ureido-glutamate functional groups bind to the active site of prostate s...
International audienceImproved bifunctional chelating agents (BFC) are required for copper-64 radiol...
The first macrocyclic bifunctional chelator incorporating propylene cross-bridge was efficiently syn...
This study investigated several somatostatin analogues labeled with copper-64 for imaging and target...
A bifunctional ligand that can rapidly form a stable complex with a metal while conjugated to a tumo...
Because of an indisputable pharmacological advatages of radiometal-labeled compounds, a purpose of t...
International audienceWe present here the synthesis of two new bifunctionalized azachelators, no2th-...
A bifunctional chelator for stably complexing metal radionuclides to tumor-targeting molecules is cr...
Publication Date (Web): June 13, 2011The synthesis of new cage amine macrobicyclic ligands with pend...
C1 - Journal Articles RefereedThe synthesis of new cage amine macrobicyclic ligands with pendent car...
A range of new carboxylate functionalised bis(thiosemicarbazone) ligands and their Cu(II) complexes ...
New bifunctional derivatives of diacetyl-bis(4-methylthiosemicarbazone) (H(2)atsm) have been prepare...
The use of copper radioisotopes in cancer diagnosis and radionuclide therapy is possible using chela...
A new class of multifunctionalized sarcophagine derivatives was synthesized for 64Cu chelation. The ...
International audienceAbstract Three new bifunctional copper chelators based on the 1,4,7-triazacycl...
Molecules containing lysine-ureido-glutamate functional groups bind to the active site of prostate s...
International audienceImproved bifunctional chelating agents (BFC) are required for copper-64 radiol...
The first macrocyclic bifunctional chelator incorporating propylene cross-bridge was efficiently syn...
This study investigated several somatostatin analogues labeled with copper-64 for imaging and target...
A bifunctional ligand that can rapidly form a stable complex with a metal while conjugated to a tumo...
Because of an indisputable pharmacological advatages of radiometal-labeled compounds, a purpose of t...
International audienceWe present here the synthesis of two new bifunctionalized azachelators, no2th-...
A bifunctional chelator for stably complexing metal radionuclides to tumor-targeting molecules is cr...