Targeted therapy: the promising implication of mesenchymal stem cells

Mesenchymal stem cells (MSCs), or multipotent stromal cell are non-hematopoetic cells from mesoderm germline. They can be isolated from various types of tissues like bone marrow, adi- pose tissue, umbilical cord blood, chorionic villi, amniotic fluid, placenta and fetal liver or lung. Due to their self-renewal ability, targeted migration and their potential to differentiate, MSCs hold a great potential to be employed in clinical medicine. They have a capacity of differentia- tion into a variety cell lineages like osteocytes, chondrocytes, adipocytes and other cell types. Recovery of damage tissue is taking place in a treatment of fractures, cardiovascular and neu- rological disorders. Furthermore, MSCs exhibit significant affinity for tumor cells, so they can be used as carriers of anti-tumor drugs. In this bachelor thesis I discuss the current knowledge in the field of targeted therapy. Key words: targeted therapy, tumor, mesenchymal stem cell