N-Acyl and N-sulfonylhydroxymetyhylpyrroles have been synthesised and shown to inhibit α-chymotrypsin. A hydrophobic group in the N-substituent has been shown to be required for activity.Andrew D. Abell, and Brent K. Nabbshttp://www.sciencedirect.com/science/journal/0968089
This thesis examines the synthesis and proteolytic properties of a new class of latent reactive amin...
A kinetic study of inactivation of $\alpha$-chymotrypsin by enol lactones was performed. Halo enol l...
© 2017 Elsevier Ltd Inhibitors of CYP1 enzymes may play vital roles in the prevention of cancer and ...
13C NMR and mass spectrometry studies have been used to demonstrate that the inhibition of alpha-chy...
A series of dipeptide aldehydes containing different N-terminal heterocycles was prepared and assaye...
First published online 23 Jun 2016Here we describe an NMR and X-ray crystallography-based characteri...
This thesis examines the chemistry and biochemistry of hydroxyrnethylpyrroles of the type 1.9 (X = O...
179 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1985.Halo enol lactones can act as...
This thesis examines ways in which the chemical reactivity of benzimidazole-, pyrrole- or pyrrolizin...
Mechanism-based inhibitors of the serine protease $\alpha$-chymotrypsin have previously been prepare...
The diazo compound derived from N"-acetyl-L-phenylalanine methyl ester, DAPM (£-diazo-N-acetyl-...
Three new compounds (3-5) based on a dipeptide non-covalent inhibitor (1) of α-chymotrypsin have bee...
The aldehyde inhibitor Z-Ala-Ala-Phe-CHO has been synthesized and shown by 13C-NMR to react with the...
This paper deals with the design, synthesis, and evaluation of a new series of receptors for protein...
Heterocyclic-based peptidomimetics possess properties that are dictated by the chemical and physical...
This thesis examines the synthesis and proteolytic properties of a new class of latent reactive amin...
A kinetic study of inactivation of $\alpha$-chymotrypsin by enol lactones was performed. Halo enol l...
© 2017 Elsevier Ltd Inhibitors of CYP1 enzymes may play vital roles in the prevention of cancer and ...
13C NMR and mass spectrometry studies have been used to demonstrate that the inhibition of alpha-chy...
A series of dipeptide aldehydes containing different N-terminal heterocycles was prepared and assaye...
First published online 23 Jun 2016Here we describe an NMR and X-ray crystallography-based characteri...
This thesis examines the chemistry and biochemistry of hydroxyrnethylpyrroles of the type 1.9 (X = O...
179 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1985.Halo enol lactones can act as...
This thesis examines ways in which the chemical reactivity of benzimidazole-, pyrrole- or pyrrolizin...
Mechanism-based inhibitors of the serine protease $\alpha$-chymotrypsin have previously been prepare...
The diazo compound derived from N"-acetyl-L-phenylalanine methyl ester, DAPM (£-diazo-N-acetyl-...
Three new compounds (3-5) based on a dipeptide non-covalent inhibitor (1) of α-chymotrypsin have bee...
The aldehyde inhibitor Z-Ala-Ala-Phe-CHO has been synthesized and shown by 13C-NMR to react with the...
This paper deals with the design, synthesis, and evaluation of a new series of receptors for protein...
Heterocyclic-based peptidomimetics possess properties that are dictated by the chemical and physical...
This thesis examines the synthesis and proteolytic properties of a new class of latent reactive amin...
A kinetic study of inactivation of $\alpha$-chymotrypsin by enol lactones was performed. Halo enol l...
© 2017 Elsevier Ltd Inhibitors of CYP1 enzymes may play vital roles in the prevention of cancer and ...
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