Background/Aims: Age-related macular degeneration (AMD) is the primary cause of senior blindness in developed countries. Mechanisms underlying initiation and development of AMD remained known. Methods: We examined the CD4+ T cell compartments and their functions in AMD patients. Results: AMD patients presented significantly higher frequencies of interferon (IFN)-γ-expressing and interleukin (IL)-17-expressing CD4+ T cells than healthy controls. The levels of IFN-γ and IL-17 expression by CD4+ T cells were significantly higher in AMD patients. These IFN-γ-expressing Th1 cells and IL-17-expressing Th17 cells could be selectively enriched by surface CCR3+ and CCR4+CCR6+ expression, respectively. Th1 and Th17 cells from AMD patients promoted th...
Purpose Prior research in animal models has suggested that retinal macrophages play an important rol...
Age-related macular degeneration (AMD) is a multifactorial disease that represents the most common c...
Copyright © 2014 Serge Camelo.This is an open access article distributed under the Creative Commons ...
Purpose: Local and possibly systemic inflammation play important roles in AMD; understanding the pro...
Citation: Zhao Z, Xu P, Jie Z, et al. cd T cells as a major source of IL-17 production during age-de...
Age-related macular degeneration is the leading cause of vision loss in the over 50?s in developed c...
Age-related macular degeneration (AMD) is a disease of the retina and the leading cause of vision lo...
<div><p>Age-related macular degeneration (AMD) is a common yet complex retinal degeneration that cau...
Age-related macular degeneration (AMD) is a major disease affecting central vision, but the pathogen...
Age-related macular degeneration (AMD) is a neurodegenerative disease of the retina and the leading ...
Age-related macular degeneration (AMD) is a neurodegenerative disease characterized by retinal cell ...
Th17 cells have been implicated in the pathogenesis of numerous inflammatory and autoimmune conditio...
Macrophages are involved in low-grade inflammation in diabetes, and play pathogenic roles in prolife...
Inflammation is a key underlying factor of age-related macular degeneration (AMD) and inflammasome a...
Age-related macular degeneration (AMD) is a multifactorial disease that represents the most common c...
Purpose Prior research in animal models has suggested that retinal macrophages play an important rol...
Age-related macular degeneration (AMD) is a multifactorial disease that represents the most common c...
Copyright © 2014 Serge Camelo.This is an open access article distributed under the Creative Commons ...
Purpose: Local and possibly systemic inflammation play important roles in AMD; understanding the pro...
Citation: Zhao Z, Xu P, Jie Z, et al. cd T cells as a major source of IL-17 production during age-de...
Age-related macular degeneration is the leading cause of vision loss in the over 50?s in developed c...
Age-related macular degeneration (AMD) is a disease of the retina and the leading cause of vision lo...
<div><p>Age-related macular degeneration (AMD) is a common yet complex retinal degeneration that cau...
Age-related macular degeneration (AMD) is a major disease affecting central vision, but the pathogen...
Age-related macular degeneration (AMD) is a neurodegenerative disease of the retina and the leading ...
Age-related macular degeneration (AMD) is a neurodegenerative disease characterized by retinal cell ...
Th17 cells have been implicated in the pathogenesis of numerous inflammatory and autoimmune conditio...
Macrophages are involved in low-grade inflammation in diabetes, and play pathogenic roles in prolife...
Inflammation is a key underlying factor of age-related macular degeneration (AMD) and inflammasome a...
Age-related macular degeneration (AMD) is a multifactorial disease that represents the most common c...
Purpose Prior research in animal models has suggested that retinal macrophages play an important rol...
Age-related macular degeneration (AMD) is a multifactorial disease that represents the most common c...
Copyright © 2014 Serge Camelo.This is an open access article distributed under the Creative Commons ...