BACKGROUND AND AIM: Susceptibility to organ damage induced by alcohol may be due to inherited variation (polymorphism) in ethanol-metabolizing enzymes, or to polymorphisms affecting free radical or lipid metabolism mediated by enzymes such as glutathione S-transferases and apolipoprotein E. The aim was to compare the genotype frequencies of alcohol dehydrogenase-2 (ADH2), ADH3, aldehyde dehydrogenase-2 (ALDH2), cytochrome P450-2E1 (CYP2E1), glutathione S-transferase-M1 (GSTM1), GSTT1, and apolipoprotein E in patients with alcoholic cirrhosis and alcoholic chronic pancreatitis to those in control groups. PATIENTS AND METHODS: The case–control study was restricted to Caucasian adults: 57 with alcoholic cirrhosis, 71 with alcoholic chronic pan...
The observation that only a minority of heavy drinkers develop pancreatitis has prompted an intensiv...
The present study investigated the genetic contribution to alcohol dependence (AD) using genome-wide...
BACKGROUND: Chronic pancreatitis (CP) is an inflammatory disease that in some patients leads to exoc...
AIMS: Alcohol misuse is now regarded as an important risk factor for development of chronic pancreat...
AbstractBackground and aims. Chronic pancreatitis develops in 5–10% of alcohol addicts. In developed...
Background: Alcoholic cirrhosis constitutes a major public health problem in the world where ADH1B, ...
Abstract — Aim: To find the ADH3 genotypes in the Polish population likely to be responsible for hig...
Alcohol-related liver disease (ARLD) is a major public health issue caused by excessive alcohol cons...
Alcohol-related liver disease (ARLD) is a major public health issue caused by excessive alcohol cons...
Case-control studies that have investigated the association between alcoholism and alcohol-induced l...
The aim of study was to detect the genetic factors which cause the predisposition for alcoholic live...
Background: The diverse incidence of alcoholic cirrhosis around the world and the fact that not all ...
Background: The diverse incidence of alcoholic cirrhosis around the world and the fact that not all ...
Abstract — Chronic alcohol consumption is a major cause of liver cirrhosis which, however, develops ...
Aim: to detect the genetic factors predisposing alcoholic liver lesion. The main candidate genes of ...
The observation that only a minority of heavy drinkers develop pancreatitis has prompted an intensiv...
The present study investigated the genetic contribution to alcohol dependence (AD) using genome-wide...
BACKGROUND: Chronic pancreatitis (CP) is an inflammatory disease that in some patients leads to exoc...
AIMS: Alcohol misuse is now regarded as an important risk factor for development of chronic pancreat...
AbstractBackground and aims. Chronic pancreatitis develops in 5–10% of alcohol addicts. In developed...
Background: Alcoholic cirrhosis constitutes a major public health problem in the world where ADH1B, ...
Abstract — Aim: To find the ADH3 genotypes in the Polish population likely to be responsible for hig...
Alcohol-related liver disease (ARLD) is a major public health issue caused by excessive alcohol cons...
Alcohol-related liver disease (ARLD) is a major public health issue caused by excessive alcohol cons...
Case-control studies that have investigated the association between alcoholism and alcohol-induced l...
The aim of study was to detect the genetic factors which cause the predisposition for alcoholic live...
Background: The diverse incidence of alcoholic cirrhosis around the world and the fact that not all ...
Background: The diverse incidence of alcoholic cirrhosis around the world and the fact that not all ...
Abstract — Chronic alcohol consumption is a major cause of liver cirrhosis which, however, develops ...
Aim: to detect the genetic factors predisposing alcoholic liver lesion. The main candidate genes of ...
The observation that only a minority of heavy drinkers develop pancreatitis has prompted an intensiv...
The present study investigated the genetic contribution to alcohol dependence (AD) using genome-wide...
BACKGROUND: Chronic pancreatitis (CP) is an inflammatory disease that in some patients leads to exoc...