The Role of Complement, Antibody, and Tumor Necrosis Factor Alpha in the Killing of Plasmodium Falciparum By the Monocytic Cell Line THP-1

Kumaratilake, L.
Ferrante, A.
Jaeger, T.
Morris-Jones, S.

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Publication date

January 1997

DOI

10.1128/iai.65.12.5342-5345.1997

Publisher

American Society for Microbiology

Journal

Infection and Immunity

Abstract

Killing of Plasmodium falciparum blood forms by the differentiated human myelomonocytic THP-1Mo cell line was studied by a radiometric assay. Results showed that parasite killing was promoted by complement, antimalarial antibody, and the cytokines tumor necrosis factor alpha and gamma interferon. Differentiated THP-1Mo appears to be a useful monocytic cell line for the study of mechanisms of immunity to Plasmodium

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The Role of Complement, Antibody, and Tumor Necrosis Factor Alpha in the Killing of Plasmodium Falciparum By the Monocytic Cell Line THP-1

Abstract

Extracted data

The Role of Complement, Antibody, and Tumor Necrosis Factor Alpha in the Killing of Plasmodium Falciparum By the Monocytic Cell Line THP-1

Abstract

Extracted data

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