Low molecular proteins in the urine of patients with systemic lupus erythematosus Part 2. Measurement of urinary β2-microglobulin

Namba, Yoshio

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Publication date

December 1980

Publisher

岡山医学会

Journal

Okayama Igakkai Zasshi (Journal of Okayama Medical Association)

Abstract

By the use of radioimmunoassay, urinary β2-microglobulin concentration was mesured in 49 patients with systemic lupus erythematosus (SLE). The urinary β2-microglobulin was significantly elevated in SLE (p<0.01). The level of urinary β2-microglobulin did not correlate with the level of serum complement, antibody to DNA or the massive proteinuria. It was associated with urinary free light chain and the degree of renal tubular damage, but not with the glomerular lesions observed in renal biopsy specimens. The elevated level of β2-microglobulin in urine was most likely due to increased excretion of β2-microglobulin from involved tubulus or direct secretion from lymphocytes infiltrating the interstitium. The measurement of the level of urinary β...

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Low molecular proteins in the urine of patients with systemic lupus erythematosus Part 2. Measurement of urinary β2-microglobulin

Abstract

Extracted data

Low molecular proteins in the urine of patients with systemic lupus erythematosus Part 2. Measurement of urinary β2-microglobulin

Abstract

Extracted data

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