Experiments on Anaphylaxis Part 2. A Study on Passive Anaphylaxis (with a special reference to the desensitization)

Egg-white albumin was injected to rabbits previous immunized by egg-white albumin. Then the sera of these rabbits periodically taken were injected into guinea pigs. The author observed the desensitization effect of anaphylactic shock in these guinea pigs passively sensitized by such injections and arrived at the following conclusions. 1. The desensitization effect of anaphylactic shock has already taken place completely five minutes after the intravenous injection of antigen. 2. It seems that on the whole there is a parallel relationship between the strength of the anaphylactic shock and the titer of antibody in the blood. 3. The residual antigen in the blood seems to inhibit the appearance of anaphylacticshock symptoms