Studies on the Chronic Gastritis Chapter IV: On the Changes of the Gastric Mucosa in Brown-Pearce Cancer of the Rabbits

1) The mucosa is mostly thick and covered by mucus. It shows decrease and strophy of the mucosa folds, severe catarrhalic changes, and hemorrhagic erosions. 2) The metastases to the gastric mucosa occur on ralatively early days, shortest on the 14th. day. Their favorite sites are the fundus, the pyrolic region and the greater curvature side of the body. 3) There are three types in the metastatic lesions; 1. Finger-tip in size and forms ulcer. 2. Miliary in size and grayish in color. 3. Mixed type of 1. and 2. 4) The lung is the most favorite metastatic organ, excepting the stomach, and the liver and the kidney follow in order. No metastases are seen in the spleen and in the intestinal mucosa. 5) The metastases are embolic or develop in the middle layer of the mucosa or proliferate on the surface of the mucosa. 6) There is no findings to prove hematogenic metastases by the arteriography of the stomach wall. 7) The rats repeatedly administered B-P tissue extract show catarrhalic changes in the gastric mucosae