Kajian Drug-related Problems Dan Gambaran Kualitas Hidup Pasien Hemodialisis Rutin Lanjut Usia Di Rsup Dr. Sardjito YOGYAKARTA

The growth of elderly population increase fastest among the other age group. The elderly population been related to decrease renal function and other comorbidity as consequence of aging. The elderly patient with chronic kidney failure on high risk of drug-related problem (DRPs) so can attribute to patient's quality of life (QoL). The aim of this study is to know how about corelation of DRPs event and QoL of elderly patient on routine hemodialysis. This is a cross sectional study about elderly patient on routine hemodialysis on period October 22th 2012 – January 22th 2013. The study of DRPs based on medication list then been analyzed theoritically and interview to patient. The measuring of QoL use SF-36 questionaire. Assessment of adherence and drug side effect use Modified Morisky Scale and Naranjo Scale. There were 38 subjects analized, age < 70 years old (24 patients) and ≥ 70 years old (14 patients); gender men (26 patients) and women (12 patients); duration hemodialysis < 8 months (8 patients) and ≥ 8 months (30 patients); comorbidity DM (23 patients) and non DM (15 patients). There were 53 events DRPs consist of drug interactions (30 events); ADR (8 events); inproper drug selection (4 events); failure to receive drug (4 events); subtherapeutic dose (3 events); drug use without indication (2 events); overdose (1 event) and untreated indication (1 event). The result of mean QoL±SD (52.16±11.82); PCS±SD (44.52±13.91); and MCS±SD (60.27±14.00). The Pearson corelations of QoL and DRP event is not significant (p>0.05). This study show not significant correlation between DRPs event and QoL of elderly patient on routine hemodialysis