BIOCHEMICAL PROFILE OF CLARIAS GARIEPINUS EXPOSED TO SUB-LETHAL CONCENTRATIONS OF CHEMICAL ADDITIVES EFFLUENT.

Chemicals such as industrial effluents induces some level of alterations in the naturally occuring chemical composition of aquatic phase which in turn alters the behavioural, biochemistry, and general physiology of aquatic fauna among which is catfish, Clarias gariepinus. Chemical additives effluent was analysed to determine its physicochemical parameters. Part of the result conforms to the Federal Environmental Protection Agencies standard specification for effluent discharge into the aquatic environment while other parameters like TDS, TSS, and Alkalinity deviated from the standard. The fish, Clarias gariepinus was exposed to 0.25mg/L, 0.30mg/L, 0.35mg/L and 0.40mg/L concentrations of the effluent for 96 hours and the LC50 value for the acute toxicity was found to be 0.335223mg/L. The impact of long term exposure to the effluent was also evaluated through changes of selected biochemical parameters using the 20%, 10%, 5% and 2.5% of the 96-h LC50 value for 42 days.the parameters measured are glucose, total protein, cholesterol, albumin and globulin. All the parameters recorded a significant difference in their values as against the control except cholesterol. The alteration in all parameters was significantly concentration and time dependent and this could be attributed to stress behavioural response as a result of the toxicity of the effluent