Content of markers of respiratory tract remodeling in exhaled breath condensate in children suffering from bronchial asthma

Background: This study investigated to detect the content of remodeling markers of the respiratory tract in the exhaled breath condensate (EBC) of children with bronchial asthma (BA). Materials and Methods: The study was in clinical groups of children with BA were formed on the indices in sputum supernatant: the Group I - “a high risk group” of bronchial remodeling (37 patients with vascular endothelial growth factor (VEGF) more than 80 ng/ml, and matrix metalloproteinase-9 (MMP-9) more than 5.2 ng/ml), the Group II - “a moderate risk” of bronchial remodeling (41 patients with VEGF more than 80 ng/ml, and MMP-9 <5.2 ng/ml, or VEGF <80 ng/ml, and MMP-9 more than 5.2 ng/ml), the Group III - “a low risk” of bronchial remodeling (38 patients with VEGF did not achieve 80 ng/ml, and MMP-9