ABSTRACT Objective: The goal of this study was to analyze the role of aryl hydrocarbon receptor in peripheral blood CCR6+CD4+ and CD4+CD25+T cells of patients with rheumatoid arthritis. Methods: Flow cytometry was applied to determine the proportion of AhR positive cells in CCR6+CD4+T, CD4+CD25+T and peripheral blood peripheral mononuclear cells from each subject. AhR mRNA and CYP1A1 mRNA relative expression levels were tested by real-time PCR. Results: The percentage of AhR positive cells in peripheral blood mononuclear cells was higher in RA group than that in healthy cases [(35.23 ± 10.71)% vs. (18.83 ± 7.32)%, p < 0.01]. The expression levels of AhR and CYP1A1 were both increased in patients with RA while compared to controls [(3.71 ...
The aryl hydrocarbon receptor (AHR) is a transcription factor activated by ligand highly expressed o...
Evidence links aryl hydrocarbon receptor (AHR) activation to rheumatoid arthritis (RA) pathogenesis,...
<div><p>The aryl hydrocarbon receptor (AhR) has been shown to be required for optimal Thelper (Th) 1...
AbstractObjectiveThe goal of this study was to analyze the role of aryl hydrocarbon receptor in peri...
Nam Trung Nguyen,1,* Taisuke Nakahama,2,* Chi Hung Nguyen,1 Trang Thu Tran,1 Van Son Le,1 Hoang Ha C...
Rheumatoid arthritis (RA) is a chronic autoimmune disease with high morbidity and mortality. Within ...
The aryl hydrocarbon receptor (AHR) is a cytoplasmic transcription factor, which plays an essential ...
Copyright © 2014 Chaokui Wang et al.This is an open access article distributed under the Creative Co...
International audienceThe aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor...
The aryl hydrocarbon receptor (AHR) is a nuclear receptor that modulates the response to environment...
OBJECTIVE: Conflicting evidence exists regarding the suppressive capacity of Treg cells in the perip...
Background & Aims: In autoimmune hepatitis (AIH), the imbalance between regulatory T cells (Treg...
BACKGROUND: Bone marrow stromal cells produce cytokines required for the normal growth and developme...
The ligand activated transcription factor aryl hydrocarbon receptor (AhR) has been studied for many ...
The aim of this study is to show the effects of activating aryl hydrocarbon receptor (AhR) by specif...
The aryl hydrocarbon receptor (AHR) is a transcription factor activated by ligand highly expressed o...
Evidence links aryl hydrocarbon receptor (AHR) activation to rheumatoid arthritis (RA) pathogenesis,...
<div><p>The aryl hydrocarbon receptor (AhR) has been shown to be required for optimal Thelper (Th) 1...
AbstractObjectiveThe goal of this study was to analyze the role of aryl hydrocarbon receptor in peri...
Nam Trung Nguyen,1,* Taisuke Nakahama,2,* Chi Hung Nguyen,1 Trang Thu Tran,1 Van Son Le,1 Hoang Ha C...
Rheumatoid arthritis (RA) is a chronic autoimmune disease with high morbidity and mortality. Within ...
The aryl hydrocarbon receptor (AHR) is a cytoplasmic transcription factor, which plays an essential ...
Copyright © 2014 Chaokui Wang et al.This is an open access article distributed under the Creative Co...
International audienceThe aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor...
The aryl hydrocarbon receptor (AHR) is a nuclear receptor that modulates the response to environment...
OBJECTIVE: Conflicting evidence exists regarding the suppressive capacity of Treg cells in the perip...
Background & Aims: In autoimmune hepatitis (AIH), the imbalance between regulatory T cells (Treg...
BACKGROUND: Bone marrow stromal cells produce cytokines required for the normal growth and developme...
The ligand activated transcription factor aryl hydrocarbon receptor (AhR) has been studied for many ...
The aim of this study is to show the effects of activating aryl hydrocarbon receptor (AhR) by specif...
The aryl hydrocarbon receptor (AHR) is a transcription factor activated by ligand highly expressed o...
Evidence links aryl hydrocarbon receptor (AHR) activation to rheumatoid arthritis (RA) pathogenesis,...
<div><p>The aryl hydrocarbon receptor (AhR) has been shown to be required for optimal Thelper (Th) 1...