Inflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-binding domain and Leucine-rich Repeat containing protein), which regulate the secretion of the pro-inflammatory interleukin (IL)-1β and IL-18 cytokines. Monocytes and macrophages, the main cells expressing the inflammasome genes, adapt to their surrounding microenvironment by a phenotypic polarization towards a pro-inflammatory M1 phenotype that promotes inflammation or an anti-inflammatory M2 phenotype important for resolution of inflammation. Despite the importance of inflammasomes in health and disease, little is known about inflammasome gene expression in relevant human cells and the impact of monocyte and macrophage polarization in inflammasome gene expressi...
Circulating monocytes are recruited to tissues, where they differentiate to macrophages and take par...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
International audienceInflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-...
International audienceInflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-...
<div><p>Inflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-binding domain...
<p>(A) Western blot analysis from total cell lysates of M0, M1 or M2 macrophages in the presence or ...
In pulmonary diseases such as asthma and chronic obstructive pulmonary disease, macrophages orchestr...
In pulmonary diseases such as asthma and chronic obstructive pulmonary disease, macrophages orchestr...
Objective. Traumatic injury or severe surgery leads to a profound immune response with a diminished ...
Objective. Traumatic injury or severe surgery leads to a profound immune response with a diminished ...
Macrophages are a central component of innate immunity that play an important role in the defense of...
Objective. Traumatic injury or severe surgery leads to a profound immune response with a diminished ...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
Circulating monocytes are recruited to tissues, where they differentiate to macrophages and take par...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
International audienceInflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-...
International audienceInflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-...
<div><p>Inflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-binding domain...
<p>(A) Western blot analysis from total cell lysates of M0, M1 or M2 macrophages in the presence or ...
In pulmonary diseases such as asthma and chronic obstructive pulmonary disease, macrophages orchestr...
In pulmonary diseases such as asthma and chronic obstructive pulmonary disease, macrophages orchestr...
Objective. Traumatic injury or severe surgery leads to a profound immune response with a diminished ...
Objective. Traumatic injury or severe surgery leads to a profound immune response with a diminished ...
Macrophages are a central component of innate immunity that play an important role in the defense of...
Objective. Traumatic injury or severe surgery leads to a profound immune response with a diminished ...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
Circulating monocytes are recruited to tissues, where they differentiate to macrophages and take par...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...
International audienceMonocytes/macrophages (MΦ), considered as plastic cells, can differentiate int...