TAR DNA-binding protein 43 (TDP-43) is a main constituent of cytoplasmic aggregates in neuronal and glial cells in cases of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. We have previously demonstrated that adenovirus-transduced artificial TDP-43 cytoplasmic aggregates formation is enhanced by proteasome inhibition in vitro and in vivo. However, the relationship between cytoplasmic aggregate formation and cell death remains unclear. In the present study, rat neural stem cell lines stably transfected with EGFP- or Sirius-expression vectors under the control of tubulin beta III, glial fibrillary acidic protein, or 2',3'-cyclic nucleotide 3'-phosphodiesterase promoter were differentiated into neurons, astrocytes, and oli...
Transactivating DNA-binding protein-43 (TDP-43) deposits represent a typical finding in almost all A...
TAR DNA-binding protein of 43 kDa (TDP-43) is the major component protein of inclusions found in bra...
TDP-43 is pathologically and genetically with associated amyotrophic lateral sclerosis and frontotem...
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are characterized b...
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are characterized b...
AbstractInclusions of Tar DNA- binding protein 43 (TDP-43) are a pathological hallmark of amyotrophi...
The transactive response DNA-binding protein (TDP-43) is a major component of the abnormal intracell...
Amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin-positive inclusio...
TAR DNA binding protein of 43 kDa (TDP-43) has been implicated in the pathogenesis of amyotrophic la...
Aggregation of the RNA-binding protein TAR DNA-binding protein 43 (TDP-43) is the key neuropathologi...
The transactive response DNA-binding protein (TDP-43) is a major component of the abnormal intracell...
Neurodegenerative disorders: Spread of misfolded protein aggregates Further research is needed to de...
Transactive response DNA-binding protein 43 kD (TDP-43) is an aggregation-prone prion-like domain-co...
Background: TAR DNA-binding protein 43 (TDP-43) is a protein that is involved in th...
<div><p>TAR DNA-binding protein 43 (TDP-43) is a major component in aggregates of ubiquitinated prot...
Transactivating DNA-binding protein-43 (TDP-43) deposits represent a typical finding in almost all A...
TAR DNA-binding protein of 43 kDa (TDP-43) is the major component protein of inclusions found in bra...
TDP-43 is pathologically and genetically with associated amyotrophic lateral sclerosis and frontotem...
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are characterized b...
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are characterized b...
AbstractInclusions of Tar DNA- binding protein 43 (TDP-43) are a pathological hallmark of amyotrophi...
The transactive response DNA-binding protein (TDP-43) is a major component of the abnormal intracell...
Amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin-positive inclusio...
TAR DNA binding protein of 43 kDa (TDP-43) has been implicated in the pathogenesis of amyotrophic la...
Aggregation of the RNA-binding protein TAR DNA-binding protein 43 (TDP-43) is the key neuropathologi...
The transactive response DNA-binding protein (TDP-43) is a major component of the abnormal intracell...
Neurodegenerative disorders: Spread of misfolded protein aggregates Further research is needed to de...
Transactive response DNA-binding protein 43 kD (TDP-43) is an aggregation-prone prion-like domain-co...
Background: TAR DNA-binding protein 43 (TDP-43) is a protein that is involved in th...
<div><p>TAR DNA-binding protein 43 (TDP-43) is a major component in aggregates of ubiquitinated prot...
Transactivating DNA-binding protein-43 (TDP-43) deposits represent a typical finding in almost all A...
TAR DNA-binding protein of 43 kDa (TDP-43) is the major component protein of inclusions found in bra...
TDP-43 is pathologically and genetically with associated amyotrophic lateral sclerosis and frontotem...