Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy.
- Perwitasari, Dyah A
- Wessels, Judith A M
- van der Straaten, Robert J H M
- Baak-Pablo, Renee F
- Mustofa, Mustofa
- Hakimi, Mohammad
- Nortier, Johann W R
- Gelderblom, Hans
- Guchelaar, Henk-Jan
Publication date
October 2011
DOI ISSN
0368-2811 Language
English Citation count (estimate)
17Abstract
Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and vomiting
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