An evaluation of efficiency rate of CK – MB test in comparison with total CPK test in diagnosis of patients with acute myocardial Infarction

Introduction : Acute myocardial infarction (AMI) is one of the most common and important causes of mortality and morbidity in human beings,today. Certainly , Rapid Diagnosis in Patients with AMI is very important . From valuable diagnostic methods is checking up serum cardiac enzymes . The use of troponin ( cTn I , T ) and CK – MB is specific in Rapid diagnosis in AMI . In this study , we compared the total CPK and CK– MB for rate of efficiency in AMI diagnosis in Ardabil Bouali hospital . Methods and Materials : This study was done in descriptive – analytic method in approximately one year duration . In patients with chest pain , after recurrent clinical examinations and serial ECGs , AMI was diagnosed , and we compared the results of serum levels of total CPK and CK – MB , then the data were gathered and analyzed by statistical methods . Results: In this search , totally 258 cases with AMI were studied that 61 patients were ignored and 197 cases entered in the study . From 197 patients , in 157 cases , level of total CPK and Ck – MB were high , but in 26 patients , total CPK was normal and from these 26 cases , in 16 cases (%8.12 of all ) CK – MBI , was high . From 197 patients in 14 cases CK – MB was normal that 5 of them had high total CPK . Conclusion: With attention to results. it seems that CK– MB test in suspicious patients is essential in diagnosis of AMI. In addition , both of CK – MB and total CPK test in 2.53% cases can be helpful , but performing of two tests simultaneously in one patient is not economical