In order to investigate gas-phase fragmentation reactions of phosphorylated peptide ions, matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization (ESI) tandem mass (MS/MS) spectra were recorded from synthetic phosphopeptides and from phosphopeptides isolated from natural sources. MALDI-TOF/TOF (TOF: time-of-flight) spectra of synthetic arginine-containing phosphopeptides revealed a significant increase of y ions resulting from bond cleavages on the C-terminal side of phosphothreonine or phosphoserine. The same effect was found in ESI-MS/MS spectra recorded from the singly charged but not from the doubly charged ions of these phosphopeptides. ESI-MS/MS spectra of doubly charged phosphopeptides containing two arginine ...
Protein methylation at arginine residues is a prevalent posttranslational modification in eukaryotic...
Vacuum UV photodissociation tandem mass spectra of singly charged arginine-terminated phosphopeptide...
AbstractMass spectrometry of charged derivatives of peptides has been a growing area of interest in ...
AbstractAn investigation of phosphate loss from phosphopeptide ions was conducted, using both atmosp...
AbstractA systematic study of the fragmentation pattern of phosphopeptides in an electrospray (ESI) ...
AbstractWe have previously shown that the presence of phosphorylation can inhibit detection of elect...
Pioneering work by among others the groups of Hunt and Mann at the start of this century opened up t...
AbstractThe fragmentation of peptides, to which a positive charge is attached at the N-terminus, was...
Protein identification is routinely accomplished by peptide sequencing using mass spectrometry (MS) ...
The effect of the basic residue on the energetics, dynamics, and mechanisms of backbone fragmentatio...
AbstractAn investigation of phosphate loss from sodium-cationized phosphotyrosine containing peptide...
Reversible phosphorylation is a key event in many biological processes and is therefore a much studi...
Electrospray mass spectrometry (ESI-MS) has become the tool of choice for the study of noncovalent c...
AbstractProtein methylation at arginine residues is a prevalent posttranslational modification in eu...
International audienceN-terminal derivatization of proteins with permanently positive charged reagen...
Protein methylation at arginine residues is a prevalent posttranslational modification in eukaryotic...
Vacuum UV photodissociation tandem mass spectra of singly charged arginine-terminated phosphopeptide...
AbstractMass spectrometry of charged derivatives of peptides has been a growing area of interest in ...
AbstractAn investigation of phosphate loss from phosphopeptide ions was conducted, using both atmosp...
AbstractA systematic study of the fragmentation pattern of phosphopeptides in an electrospray (ESI) ...
AbstractWe have previously shown that the presence of phosphorylation can inhibit detection of elect...
Pioneering work by among others the groups of Hunt and Mann at the start of this century opened up t...
AbstractThe fragmentation of peptides, to which a positive charge is attached at the N-terminus, was...
Protein identification is routinely accomplished by peptide sequencing using mass spectrometry (MS) ...
The effect of the basic residue on the energetics, dynamics, and mechanisms of backbone fragmentatio...
AbstractAn investigation of phosphate loss from sodium-cationized phosphotyrosine containing peptide...
Reversible phosphorylation is a key event in many biological processes and is therefore a much studi...
Electrospray mass spectrometry (ESI-MS) has become the tool of choice for the study of noncovalent c...
AbstractProtein methylation at arginine residues is a prevalent posttranslational modification in eu...
International audienceN-terminal derivatization of proteins with permanently positive charged reagen...
Protein methylation at arginine residues is a prevalent posttranslational modification in eukaryotic...
Vacuum UV photodissociation tandem mass spectra of singly charged arginine-terminated phosphopeptide...
AbstractMass spectrometry of charged derivatives of peptides has been a growing area of interest in ...