Add to ORKGThe term 'sclerosing diseases of the skin' comprises specific dermatological entities, which have fibrotic changes of the skin in common. These diseases mostly manifest in different clinical subtypes according to cutaneous and extracutaneous involvement and can sometimes be difficult to distinguish from each other. The present guideline focuses on characteristic clinical and histopathological features, diagnostic scores and the serum autoantibodies most useful for differential diagnosis. In addition, current strategies in the first- and advanced-line therapy of sclerosing skin diseases are addressed in detail. Part 1 of this guideline provides clinicians with an overview of the diagnosis and treatment of localized scleroderma (morphea), and...
Retinal manifestations have been described in several neurodegenerative insults and disorders. The s...
Astrocytes might play an important role in demyelinating diseases such as multiple sclerosis (MS) si...
Rheumatoid Arthritis (RA) is the commonest inflammatory polyarthritis in the UK, and is associated w...
The term 'sclerosing diseases of the skin' comprises specific dermatological entities which have fib...
Background: We have insufficient diagnostic tools to capture and anticipate the course of multiple s...
Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) are common neurodegenerative disord...
Objective: To evaluate safety, tolerability and feasibility of long-term treatment with Granulocyt...
The exact mechanism for the pathogenesis of amyotrophic lateral sclerosis (ALS) is not known. Howeve...
The von Hippel-lindau (VHL) disease is a dominantly inherited neoplastic disorder which predisposes ...
Alzheimer’s disease (AD) is the most common late-onset neurodegenerative disorder and cause of demen...
The work described below is divided into two parts. In the first chapter, the development of a nov...
Approximately 50% of all primary open-angle glaucoma (POAG) is familial. Investigation of clinical ...
Staphylococcus aureus is a commensal and pathogen of humans and other animals. Disease with S. aureu...
Imatinib mesylate (imatinib) represents a potent molecularly targeted therapy against the oncogenic ...
Plant diseases account for more than 40% of crop losses. Breeding for disease resistance is the most...
Retinal manifestations have been described in several neurodegenerative insults and disorders. The s...
Astrocytes might play an important role in demyelinating diseases such as multiple sclerosis (MS) si...
Rheumatoid Arthritis (RA) is the commonest inflammatory polyarthritis in the UK, and is associated w...
The term 'sclerosing diseases of the skin' comprises specific dermatological entities which have fib...
Background: We have insufficient diagnostic tools to capture and anticipate the course of multiple s...
Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) are common neurodegenerative disord...
Objective: To evaluate safety, tolerability and feasibility of long-term treatment with Granulocyt...
The exact mechanism for the pathogenesis of amyotrophic lateral sclerosis (ALS) is not known. Howeve...
The von Hippel-lindau (VHL) disease is a dominantly inherited neoplastic disorder which predisposes ...
Alzheimer’s disease (AD) is the most common late-onset neurodegenerative disorder and cause of demen...
The work described below is divided into two parts. In the first chapter, the development of a nov...
Approximately 50% of all primary open-angle glaucoma (POAG) is familial. Investigation of clinical ...
Staphylococcus aureus is a commensal and pathogen of humans and other animals. Disease with S. aureu...
Imatinib mesylate (imatinib) represents a potent molecularly targeted therapy against the oncogenic ...
Plant diseases account for more than 40% of crop losses. Breeding for disease resistance is the most...
Retinal manifestations have been described in several neurodegenerative insults and disorders. The s...
Astrocytes might play an important role in demyelinating diseases such as multiple sclerosis (MS) si...
Rheumatoid Arthritis (RA) is the commonest inflammatory polyarthritis in the UK, and is associated w...