Add to ORKGProspective studies in cancer epidemiology have con-served their study design over the last decades. In this context, current epidemiologic studies investigating gene-environment interactions are based on biobank for the analysis of genetic variation and biomarkers, using notified cancer as outcome. These studies result from the use of high-throughput technologies rather than from the development of novel design strategies. In this article, we propose the globolomic design to run integrated analyses of cancer risk covering the major-omics in blood and tumor tissue. We defined this design as an extension of the existing prospective design by collecting tissue and blood samples at time of diagnosis, including biological material suitable fo
Advances in genomics and related fields are promising tools for risk assessment, early detection, an...
Classical epidemiologic studies have made seminal contributions to identifying the etiology of most ...
Molecular epidemiology is the integration of molecular biologic techniques into epidemiologic study....
It is becoming evident that holistic perspectives toward cancer are crucial in deciphering the overw...
The development and progression of cancer, a collection of diseases with complex genetic architectur...
BACKGROUND: With the arrival of the postgenomic era, there is increasing interest in the discovery o...
The development of the sequencing technologies allowed the generation of huge amounts of molecular d...
The increasing use of omics data in epidemiology enables many novel study designs, but also introduc...
The application of state-of-the-art proteomics and func-tional genomics technologies to the study of...
With the arrival of the postgenomic era, there is increasing interest in the discovery of biomarkers...
Cancer is a complex disease and it remains the second leading cause of death in the United States. C...
In spite of decades of epidemiological research, the etiology and causal patterns for many common di...
For -omics investigations to achieve their aspired potential, fundamental aspects relating to the st...
Malignant tumors remain one of the leading causes of mortality with over 8.2 million deaths worldwid...
Introduction The introduction of high-throughput technologies, also called -omics te...
Advances in genomics and related fields are promising tools for risk assessment, early detection, an...
Classical epidemiologic studies have made seminal contributions to identifying the etiology of most ...
Molecular epidemiology is the integration of molecular biologic techniques into epidemiologic study....
It is becoming evident that holistic perspectives toward cancer are crucial in deciphering the overw...
The development and progression of cancer, a collection of diseases with complex genetic architectur...
BACKGROUND: With the arrival of the postgenomic era, there is increasing interest in the discovery o...
The development of the sequencing technologies allowed the generation of huge amounts of molecular d...
The increasing use of omics data in epidemiology enables many novel study designs, but also introduc...
The application of state-of-the-art proteomics and func-tional genomics technologies to the study of...
With the arrival of the postgenomic era, there is increasing interest in the discovery of biomarkers...
Cancer is a complex disease and it remains the second leading cause of death in the United States. C...
In spite of decades of epidemiological research, the etiology and causal patterns for many common di...
For -omics investigations to achieve their aspired potential, fundamental aspects relating to the st...
Malignant tumors remain one of the leading causes of mortality with over 8.2 million deaths worldwid...
Introduction The introduction of high-throughput technologies, also called -omics te...
Advances in genomics and related fields are promising tools for risk assessment, early detection, an...
Classical epidemiologic studies have made seminal contributions to identifying the etiology of most ...
Molecular epidemiology is the integration of molecular biologic techniques into epidemiologic study....